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Table 2 Detailed results of microarray platform of the transferred blastocysts

From: The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers

Family

The number of biopsied blastocysts

Grade of blastocysts

Molecular karyotype

Results of PGH

Transferred blastocysts

Karyotype of amniotic fluid

Consistency?

    

Family membera

Unbalanced embryosb

   

1

7

6BB

(1-22,X)*2

Carrier

NA

Embryo-1

46,XX,t(5;22)(q33;q12)

Yes

2

4

5 BC

(1-22,X)*2

Normal

Normal

Embryo-4

46,XX

Yes

3

3

5BB

(1-22)*2, (XY)*1

Carrier

NA

Embryo-6

46,XY,t(12;22)(p12;q13)

Yes

4

6

5BB

(1-22,X)*2

Normal

NA

Embryo-1

46,XX

Yes

5

6

5AB

(1-22,X)*2

Carrier

Carrier

Embryo-1

46,XX,t(1; 19) (q12;p13)

Yes

6

6

5 BC

(1-22,X)*2

Carrier

Carrier

Embryo-9

45,XX, rob(14; 21)(q10;q10)

Yes

7

8

5 BC

(1-22,X)*2

Normal

Normal

Embryo-6

46,XX

Yes

8

3

5BB

(1-22)*2, (XY)*1

Carrier

NA

Embryo-2

45,XY,der(14;15)(q10;q10)

Yes

9

3

5AB

(1-22,X)*2

Normal

NA

Embryo-4

46,XX

Yes

10

12

5 AC

(1-22,X)*2

NA

Carrier

Embryo-1-5

No pregnancy

NA

  

5BB

(1-22,X)*2

NA

Carrier

Embryo-3-4

No pregnancy

NA

  

5 BC

(1-22)*2, (XY)*1

NA

Normal

Embryo-3-1

46,XY

Yes

11

12

5 BC

(1-22,X)*2

NA

Normal

Embryo-12

46,XX

Yes

  1. NA = not available
  2. aIn family1-9, the family member was used as a reference; in family10-11, the unbalanced embryo was used as a reference
  3. bIn family2, embryo-1, embryo-4 and embryo-9 were included; In family5, embryo-3 was included; In family6, embryo-4 was included; In family7, embryo-13 was included; In other families, the unbalanced embryos couldn’t be used as reference