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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Chromosome 9p copy number gains involving PD-L1 are associated with a specific proliferation and immune-modulating gene expression program active across major cancer types

Fig. 2

Heatmap of the top list of 75 strongly and recurrent differentially expressed genes (as defined in methods) between tumors with and without PD-L1 CNGs. Significant (p < 0.05) changes are highlighted as colored boxes. The genes are annotated to the following three groups: A = gene located on chromosome 9p, B = gene plays a role in cell cycle regulation, C = gene is implicated in immune system processes

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