TY - JOUR AU - Iorio, F. AU - Rittman, T. AU - Ge, H. PY - 2013 DA - 2013// TI - Transcriptional data: a new gateway to drug repositioning? JO - Drug Discov today VL - 18 UR - https://doi.org/10.1016/j.drudis.2012.07.014 DO - 10.1016/j.drudis.2012.07.014 ID - Iorio2013 ER - TY - JOUR AU - Booth, B. AU - Zemmel, R. PY - 2004 DA - 2004// TI - Prospects for productivity JO - Nat Rev Drug Discov VL - 3 UR - https://doi.org/10.1038/nrd1384 DO - 10.1038/nrd1384 ID - Booth2004 ER - TY - JOUR AU - Li, J. AU - Zheng, S. AU - Chen, B. PY - 2016 DA - 2016// TI - A survey of current trends in computational drug repositioning JO - Brief Bioinforma VL - 17 UR - https://doi.org/10.1093/bib/bbv020 DO - 10.1093/bib/bbv020 ID - Li2016 ER - TY - JOUR AU - Chiang, A. P. AU - Butte, A. J. PY - 2009 DA - 2009// TI - Systematic evaluation of drug-disease relationships to identify leads for novel drug uses JO - Clin Pharmacol Ther VL - 86 UR - https://doi.org/10.1038/clpt.2009.103 DO - 10.1038/clpt.2009.103 ID - Chiang2009 ER - TY - JOUR AU - Ashburn, T. T. AU - Thor, K. B. PY - 2004 DA - 2004// TI - Drug repositioning: identifying and developing new uses for existing drugs JO - Nat Rev Drug Discov VL - 3 UR - https://doi.org/10.1038/nrd1468 DO - 10.1038/nrd1468 ID - Ashburn2004 ER - TY - JOUR AU - Novac, N. PY - 2013 DA - 2013// TI - Challenges and opportunities of drug repositioning JO - Trends Pharmacol Sci VL - 34 UR - https://doi.org/10.1016/j.tips.2013.03.004 DO - 10.1016/j.tips.2013.03.004 ID - Novac2013 ER - TY - JOUR AU - Varothai, S. AU - Bergfeld, W. F. PY - 2014 DA - 2014// TI - Androgenetic alopecia: an evidence-based treatment update JO - Am J Clin Dermatol VL - 15 UR - https://doi.org/10.1007/s40257-014-0077-5 DO - 10.1007/s40257-014-0077-5 ID - Varothai2014 ER - TY - JOUR AU - Segura-Aguilar, J. AU - Muñoz, P. AU - Paris, I. PY - 2016 DA - 2016// TI - Aminochrome as new preclinical model to find new pharmacological treatment that stop the development of parkinson’s disease JO - Curr Med Chem VL - 23 UR - https://doi.org/10.2174/0929867323666151223094103 DO - 10.2174/0929867323666151223094103 ID - Segura-Aguilar2016 ER - TY - JOUR AU - Harrison, C. PY - 2011 DA - 2011// TI - Drug repositioning: Genetic signatures uncover new uses JO - Nat Rev Drug Discov VL - 10 UR - https://doi.org/10.1038/nrd3565 DO - 10.1038/nrd3565 ID - Harrison2011 ER - TY - JOUR AU - Sirota, M. AU - Dudley, J. T. AU - Kim, J. PY - 2011 DA - 2011// TI - Discovery and preclinical validation of drug indications using compendia of public gene expression data JO - Sci Transl Med VL - 3 UR - https://doi.org/10.1126/scitranslmed.3001318 DO - 10.1126/scitranslmed.3001318 ID - Sirota2011 ER - TY - JOUR AU - Jahchan, N. S. AU - Dudley, J. T. AU - Mazur, P. K. PY - 2013 DA - 2013// TI - A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors JO - Cancer Discov VL - 3 UR - https://doi.org/10.1158/2159-8290.CD-13-0183 DO - 10.1158/2159-8290.CD-13-0183 ID - Jahchan2013 ER - TY - JOUR AU - Andronis, C. AU - Sharma, A. AU - Virvilis, V. PY - 2011 DA - 2011// TI - Literature mining, ontologies and information visualization for drug repurposing JO - Brief Bioinforma VL - 12 UR - https://doi.org/10.1093/bib/bbr005 DO - 10.1093/bib/bbr005 ID - Andronis2011 ER - TY - JOUR AU - Weeber, M. AU - Kors, J. A. AU - Mons, B. PY - 2005 DA - 2005// TI - Online tools to support literature-based discovery in the life sciences JO - Brief Bioinforma VL - 6 UR - https://doi.org/10.1093/bib/6.3.277 DO - 10.1093/bib/6.3.277 ID - Weeber2005 ER - TY - STD TI - Ahlers CB, Hristovski D, Kilicoglu H, et al.Using the literature-based discovery paradigm to investigate drug mechanisms. In: AMIA: 2007. ID - ref14 ER - TY - JOUR AU - Gottlieb, A. AU - Stein, G. Y. AU - Ruppin, E. PY - 2011 DA - 2011// TI - Predict: a method for inferring novel drug indications with application to personalized medicine JO - Mol Syst Biol VL - 7 UR - https://doi.org/10.1038/msb.2011.26 DO - 10.1038/msb.2011.26 ID - Gottlieb2011 ER - TY - JOUR AU - Chen, H. AU - Zhang, H. AU - Zhang, Z. PY - 2015 DA - 2015// TI - Network-based inference methods for drug repositioning JO - Comput Math Methods Med VL - 2015 ID - Chen2015 ER - TY - JOUR AU - Liang, X. AU - Zhang, P. AU - Yan, L. PY - 2017 DA - 2017// TI - Lrssl: predict and interpret drug-disease associations based on data integration using sparse subspace learning JO - Bioinformatics (Oxford, England) VL - 33 ID - Liang2017 ER - TY - JOUR AU - Cheng, F. AU - Liu, C. AU - Jiang, J. PY - 2012 DA - 2012// TI - Prediction of drug-target interactions and drug repositioning via network-based inference JO - PLoS Compututational Biol VL - 8 UR - https://doi.org/10.1371/journal.pcbi.1002503 DO - 10.1371/journal.pcbi.1002503 ID - Cheng2012 ER - TY - JOUR AU - Emig, D. AU - Ivliev, A. AU - Pustovalova, O. PY - 2013 DA - 2013// TI - Drug target prediction and repositioning using an integrated network-based approach JO - PLoS ONE VL - 8 UR - https://doi.org/10.1371/journal.pone.0060618 DO - 10.1371/journal.pone.0060618 ID - Emig2013 ER - TY - JOUR AU - Wang, W. AU - Yang, S. AU - Li, J. PY - 2013 DA - 2013// TI - Drug target predictions based on heterogeneous graph inference JO - Biocomputing VL - 2013 ID - Wang2013 ER - TY - JOUR AU - Wang, W. AU - Yang, S. AU - Zhang, X. PY - 2014 DA - 2014// TI - Drug repositioning by integrating target information through a heterogeneous network model JO - Bioinformatics VL - 30 UR - https://doi.org/10.1093/bioinformatics/btu403 DO - 10.1093/bioinformatics/btu403 ID - Wang2014 ER - TY - JOUR AU - Wen, Z. AU - Chen, Y. AU - Feng, L. AU - Fei, L. AU - Gang, T. AU - Li, X. PY - 2017 DA - 2017// TI - Predicting potential drug-drug interactions by integrating chemical, biological, phenotypic and network data JO - Bmc Bioinformatics VL - 18 UR - https://doi.org/10.1186/s12859-016-1415-9 DO - 10.1186/s12859-016-1415-9 ID - Wen2017 ER - TY - JOUR AU - Knox, C. AU - Law, V. AU - Jewison, T. PY - 2011 DA - 2011// TI - Drugbank 3.0: a comprehensive resource for ‘omics’ research on drugs JO - Nucleic Acids Res VL - 39 UR - https://doi.org/10.1093/nar/gkq1126 DO - 10.1093/nar/gkq1126 ID - Knox2011 ER - TY - JOUR AU - Griffith, M. AU - Griffith, O. L. AU - Coffman, A. C. PY - 2013 DA - 2013// TI - Dgidb - mining the druggable genome for personalized medicine JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2689 DO - 10.1038/nmeth.2689 ID - Griffith2013 ER - TY - JOUR AU - Licata, L. AU - Briganti, L. AU - Peluso, D. PY - 2012 DA - 2012// TI - Mint, the molecular interaction database: 2012 update JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gkr930 DO - 10.1093/nar/gkr930 ID - Licata2012 ER - TY - JOUR AU - Consortium, U. PY - 2017 DA - 2017// TI - Uniprot: the universal protein knowledgebase JO - Nucleic Acids Res VL - 45 UR - https://doi.org/10.1093/nar/gkw1099 DO - 10.1093/nar/gkw1099 ID - Consortium2017 ER - TY - JOUR AU - Hamosh, A. AU - Scott, A. F. AU - Amberger, J. S. PY - 2005 DA - 2005// TI - Online mendelian inheritance in man (omim), a knowledgebase of human genes and genetic disorders JO - Nucleic Acids Res VL - 33 ID - Hamosh2005 ER - TY - JOUR AU - Weininger, D. PY - 1988 DA - 1988// TI - Smiles, a chemical language and information system. 1. introduction to methodology and encoding rules JO - J Chem Inf Comput Sci VL - 28 UR - https://doi.org/10.1021/ci00057a005 DO - 10.1021/ci00057a005 ID - Weininger1988 ER - TY - JOUR AU - O’Boyle, N. M. AU - Banck, M. AU - James, C. A. AU - Morley, C. AU - Vandermeersch, T. AU - Hutchison, G. R. PY - 2011 DA - 2011// TI - Open babel: An open chemical toolbox JO - J Cheminformatics VL - 3 UR - https://doi.org/10.1186/1758-2946-3-33 DO - 10.1186/1758-2946-3-33 ID - O’Boyle2011 ER - TY - BOOK AU - Tanimoto, T. T. PY - 1958 DA - 1958// TI - Elementary Mathematical Theory of Classification and Prediction PB - Int Bus Machines Corp CY - Armonk ID - Tanimoto1958 ER - TY - JOUR AU - Van Driel, M. A. AU - Bruggeman, J. AU - Vriend, G. PY - 2006 DA - 2006// TI - A text-mining analysis of the human phenome JO - European J Human Genet VL - 14 UR - https://doi.org/10.1038/sj.ejhg.5201585 DO - 10.1038/sj.ejhg.5201585 ID - Van Driel2006 ER - TY - JOUR AU - Lipscomb, C. E. PY - 2000 DA - 2000// TI - Medical subject headings (mesh) JO - Bull Med Libr Assoc VL - 88 ID - Lipscomb2000 ER - TY - JOUR AU - Perlman, L. AU - Gottlieb, A. AU - Atias, N. PY - 2011 DA - 2011// TI - Combining drug and gene similarity measures for drug-target elucidation JO - J Comput Biol VL - 18 UR - https://doi.org/10.1089/cmb.2010.0213 DO - 10.1089/cmb.2010.0213 ID - Perlman2011 ER - TY - JOUR AU - Yamanishi, Y. AU - Araki, M. AU - Gutteridge, A. PY - 2008 DA - 2008// TI - Prediction of drug–target interaction networks from the integration of chemical and genomic spaces JO - Bioinformatics VL - 24 UR - https://doi.org/10.1093/bioinformatics/btn162 DO - 10.1093/bioinformatics/btn162 ID - Yamanishi2008 ER - TY - STD TI - Wu G, Liu J, Wang C. Semi-supervised graph cut algorithm for drug repositioning by integrating drug, disease and genomic associations. In: 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2016). Institute of Electrical and Electronics Engineers Inc.2016;2016:223–8. ID - ref35 ER - TY - JOUR AU - Von Luxburg, U. PY - 2007 DA - 2007// TI - A tutorial on spectral clustering JO - Stat Comput VL - 17 UR - https://doi.org/10.1007/s11222-007-9033-z DO - 10.1007/s11222-007-9033-z ID - Von Luxburg2007 ER - TY - JOUR AU - Zhou, D. AU - Bousquet, O. AU - Lal, T. N. PY - 2004 DA - 2004// TI - Learning with local and global consistency JO - Adv Neural Informa Proc Syst VL - 16 ID - Zhou2004 ER - TY - JOUR AU - Lage, K. AU - Hansen, N. T. AU - Karlberg, E. O. PY - 2008 DA - 2008// TI - A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes JO - Proc Natl Acad Sci VL - 105 UR - https://doi.org/10.1073/pnas.0810772105 DO - 10.1073/pnas.0810772105 ID - Lage2008 ER - TY - JOUR AU - Su, A. I. AU - Wiltshire, T. AU - Batalov, S. PY - 2004 DA - 2004// TI - A gene atlas of the mouse and human protein-encoding transcriptomes JO - Proc Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0400782101 DO - 10.1073/pnas.0400782101 ID - Su2004 ER - TY - JOUR AU - Huang, D. W. AU - Sherman, B. T. AU - Lempicki, R. A. PY - 2009 DA - 2009// TI - Systematic and integrative analysis of large gene lists using david bioinformatics resources JO - Nat Protoc VL - 4 UR - https://doi.org/10.1038/nprot.2008.211 DO - 10.1038/nprot.2008.211 ID - Huang2009 ER - TY - JOUR AU - Huang, D. W. AU - Sherman, B. T. AU - Lempicki, R. A. PY - 2009 DA - 2009// TI - Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists JO - Nucleic Acids Res VL - 37 UR - https://doi.org/10.1093/nar/gkn923 DO - 10.1093/nar/gkn923 ID - Huang2009 ER - TY - JOUR AU - Davis, A. P. AU - Grondin, C. J. AU - Johnson, R. J. PY - 2017 DA - 2017// TI - The comparative toxicogenomics database: update 2017 JO - Nucleic Acids Res VL - 45 UR - https://doi.org/10.1093/nar/gkw838 DO - 10.1093/nar/gkw838 ID - Davis2017 ER - TY - JOUR AU - Alpay, M. AU - Koroshetz, W. J. PY - 2006 DA - 2006// TI - Quetiapine in the treatment of behavioral disturbances in patients with huntington’s disease JO - Psychosom VL - 47 UR - https://doi.org/10.1176/appi.psy.47.1.70 DO - 10.1176/appi.psy.47.1.70 ID - Alpay2006 ER - TY - JOUR AU - Bonelli, R. M. AU - Mayr, B. M. AU - Niederwieser, G. PY - 2003 DA - 2003// TI - Ziprasidone in huntington’s disease: the first case reports JO - J Psychopharmacol VL - 17 UR - https://doi.org/10.1177/0269881103174009 DO - 10.1177/0269881103174009 ID - Bonelli2003 ER - TY - JOUR AU - Duff, K. AU - Beglinger, L. J. AU - O’Rourke, M. E. PY - 2008 DA - 2008// TI - Risperidone and the treatment of psychiatric, motor, and cognitive symptoms in huntington’s disease JO - Ann Clin Psychiatry VL - 20 UR - https://doi.org/10.1080/10401230701844802 DO - 10.1080/10401230701844802 ID - Duff2008 ER - TY - JOUR AU - Brusa, L. AU - Orlacchio, A. AU - Moschella, V. PY - 2009 DA - 2009// TI - Treatment of the symptoms of huntington’s disease: preliminary results comparing aripiprazole and tetrabenazine JO - Mov Disord VL - 24 UR - https://doi.org/10.1002/mds.22376 DO - 10.1002/mds.22376 ID - Brusa2009 ER - TY - JOUR AU - Paleacu, D. AU - Anca, M. AU - Giladi, N. PY - 2002 DA - 2002// TI - Olanzapine in huntington’s disease JO - Acta Neurol Scand VL - 105 UR - https://doi.org/10.1034/j.1600-0404.2002.01197.x DO - 10.1034/j.1600-0404.2002.01197.x ID - Paleacu2002 ER - TY - JOUR AU - Van Vugt, J. AU - Siesling, S. AU - Vergeer, M. PY - 1997 DA - 1997// TI - Clozapine versus placebo in huntington’s disease: a double blind randomised comparative study JO - J Neurol Neurosurg Psychiatr VL - 63 UR - https://doi.org/10.1136/jnnp.63.1.35 DO - 10.1136/jnnp.63.1.35 ID - Van Vugt1997 ER - TY - JOUR AU - Ardizzoni, A. AU - Boni, L. AU - Tiseo, M. PY - 2007 DA - 2007// TI - Cisplatin-versus carboplatin-based chemotherapy in first-line treatment of advanced non–small-cell lung cancer: an individual patient data meta-analysis JO - J Natl Cancer Inst VL - 99 UR - https://doi.org/10.1093/jnci/djk196 DO - 10.1093/jnci/djk196 ID - Ardizzoni2007 ER - TY - JOUR AU - Martoni, A. AU - Melotti, B. AU - Guaraldi, M. AU - Pannuti, F. PY - 1991 DA - 1991// TI - Activity of high-dose epirubicin in advanced non-small cell lung cancer JO - European J Cancer Clin Oncol VL - 27 UR - https://doi.org/10.1016/0277-5379(91)90087-T DO - 10.1016/0277-5379(91)90087-T ID - Martoni1991 ER - TY - JOUR AU - Dziadziuszko, R. AU - Ardizzoni, A. AU - Postmus, P. PY - 2003 DA - 2003// TI - Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases: a phase ii study of the eortc lung cancer group (08965) JO - European J Cancer VL - 39 UR - https://doi.org/10.1016/S0959-8049(03)00234-X DO - 10.1016/S0959-8049(03)00234-X ID - Dziadziuszko2003 ER - TY - STD TI - Pani PP, Trogu E, Amato L, Davoli M. Antidepressants for the treatment of depression in alcohol dependent individuals. The Cochrane Library. 2010. ID - ref52 ER - TY - STD TI - ClinicalTrials.gov. Disulfiram combined with lorazepam for treatment of patients with alcohol dependence and primary or secondary anxiety disorder. Technical report, ClinicalTrials.gov (NCT number:NCT00721526). 2012. ID - ref53 ER - TY - STD TI - Clinicaltrials.gov. Temozolomide for relapsed sensitive or refractory small cell lung cancer. Technical report, ClinicalTrials.gov (NCT number: NCT00740636). 2012. ID - ref54 ER - TY - JOUR AU - Rustin, G. AU - Shreeves, G. AU - Nathan, P. PY - 2010 DA - 2010// TI - A phase ib trial of ca4p (combretastatin a-4 phosphate), carboplatin, and paclitaxel in patients with advanced cancer JO - British J Cancer VL - 102 UR - https://doi.org/10.1038/sj.bjc.6605650 DO - 10.1038/sj.bjc.6605650 ID - Rustin2010 ER - TY - JOUR AU - Tadokoro, J. -. i. AU - Kakihata, K. AU - Shimazaki, M. PY - 2011 DA - 2011// TI - Post-marketing surveillance (pms) of all patients treated with irinotecan in japan: clinical experience and adr profile of 13 935 patients JO - Jpn J Clin Oncol VL - 41 UR - https://doi.org/10.1093/jjco/hyr105 DO - 10.1093/jjco/hyr105 ID - Tadokoro2011 ER - TY - JOUR AU - Yamashita, J. I. AU - Ogawa, M. AU - Shirakusa, T. PY - 1995 DA - 1995// TI - Plasma endothelin-1 as a marker for doxorubicin cardiotoxicity JO - Int J cancer VL - 62 UR - https://doi.org/10.1002/ijc.2910620509 DO - 10.1002/ijc.2910620509 ID - Yamashita1995 ER - TY - JOUR AU - Gridelli, C. AU - D’Aprile, M. AU - Curcio, C. PY - 1994 DA - 1994// TI - Carboplatin plus epirubicin plus vp-16, concurrent ‘split course’ radiotherapy and adjuvant surgery for limited small cell lung cancer JO - Lung Cancer VL - 11 UR - https://doi.org/10.1016/0169-5002(94)90285-2 DO - 10.1016/0169-5002(94)90285-2 ID - Gridelli1994 ER - TY - JOUR AU - Rastegar-Mojarad, M. AU - Ye, Z. AU - Kolesar, J. M. PY - 2015 DA - 2015// TI - Opportunities for drug repositioning from phenome-wide association studies JO - Nat Biotechnol VL - 33 UR - https://doi.org/10.1038/nbt.3183 DO - 10.1038/nbt.3183 ID - Rastegar-Mojarad2015 ER -