Table 3 Clinical and demographic information of the patients with infantile spasm
Total number | Group 1 (Patients with positive genetic cause, % within group 1) | Group 2 (Patients without positive genetic cause, % within group 2) | P-value | |
|---|---|---|---|---|
Number of subjects | 51 | 16 | 35 | |
Female | 23 | 10 (62.5) | 13 (37.1) | 0.09 |
Seizure onset (months) | 1.00 | |||
0 < n ≤ 12 months | 49 | 16 (100) | 33 (94.3) | |
12 months < n ≤ 24 months | 2 | 0 | 2 (5.7) | |
24 months < n ≤ 36 months | 0 | 0 | 0 | |
mean age (± standard deviation) | 3.2 (± 3.0) | 6.2 (± 4.4) | 0.02 | |
Global developmental delay | 41 | 14 (87.5) | 27 (77.1) | 0.47 |
Absence of eye contact | 14 | 8 (50.0) | 6 (17.1) | 0.02 |
Neonatal seizures | 9 | 5 (31.3) | 4 (11.4) | 0.12 |
Febrile seizures | 2 | 2 (12.5) | 0 | 0.09 |
Status epilepticus | 1 | 0 | 1 (2.9) | 1.00 |
Premature death | 2 | 1 (6.3) | 1 (2.9) | 0.53 |
NICU stay | 20 | 7 (43.8) | 8 (22.9) | 0.19 |