Fig. 1

Manhattan plots drawn from the association results (with correction for covariates and PCs where necessary). Plots are shown for association with (a) DBP and (b) SBP. The upper horizontal line indicates the calculated array-wide significance cutoff (p = 6.7 × 10−7) while the lower horizontal line shows the cutoff of p = 1 × 10−4. Identified regions of interest for further investigation are indicated by arrows. DACH1 – Dachshund Family Transcription Factor 1; INTS10 – integrator complex subunit 10; LPL – lipoprotein lipase; MYRF – myelin regulatory factor; NOS1AP – nitric oxide synthase 1 (neuronal) adaptor protein; POC1B – POC1 centriolar protein