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Table 1 SNVs with different MAFs whose risk alleles are minor alleles

From: Are minor alleles more likely to be risk alleles?

MAF interval Total number SNVs whose risk alleles are minor alleles Proportiona Lower limitb Upper limitb P-valuec
(0–0.1) 476 378 0.794 0.755 0.830 <  2.2E-16
(0.1–0.2) 616 389 0.631 0.592 0.670 6.8E-11
(0.2–0.3) 698 417 0.597 0.560 0.634 2.97E-07
(0.3–0.4) 723 440 0.609 0.572 0.644 5.75E-09
(0.4–0.5) 771 456 0.591 0.556 0.626 4.29E-07
  1. aProportion of SNVs whose risk alleles are minor alleles
  2. bLower and upper limits of the 95% confidence interval for the proportion as determined by the Clopper–Pearson method
  3. cP-value for the binomial test with the null hypothesis that the proportion is 0.5