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Table 3 Rare-variant association tests for genes associated with ciliopathies and subsets

From: Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects

Database

Gene list (No. of genes)

Bonferroni corrected P

Reference

Burden

SKAT

SKAT-O

Invitae

Ciliopathies (102)

1.00000

1.00000

1.00000

[26]

Joubert and Meckel-Gruber Syndromes (JBTMKS; 30)

0.39528

0.10536

0.19548

[26]

GHR

Joubert Syndrome (JBTS; 11)

0.09908

0.05076

0.08020

[27]

Meckel Syndrome (MKS; 8)

1.00000

1.00000

1.00000

[28]

  1. GHR Genetics home references, SKAT sequence kernel association test
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BMC Medical Genomics

ISSN: 1755-8794

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