Gene Symbol | rsID | Variant deleteriousness score | Case, n = 13 | Control, n = 30 | EAS, n = 504 | T1GP, n = 2504 | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
SIFT | CADD | PolyPhen2 | Freq | P | Freq | P | Freq | P | |||
CYP1A1 | rs1048943 | 0.01 | 21.9 | 0.49 | 9 (69%) | 10 (33%) | 0.0457 | 221 (44%) | 0.0902 | 568 (23%) | 0.0005 |
rs143070677 | 0.03 | 24.4 | 0.51 | 1 (8%) | 1 (3%) | 0.5183 | 1 (0.2%) | 0.0497 | 1 (0.04%) | 0.0103 | |
rs4646422 | 0.08 | 24.0 | 0.19 | 4 (31%) | 12 (40%) | 0.7349 | 111 (22%) | 0.4986 | 116 (5%) | 0.0025 | |
CYP8B1 | rs202192572 | 0.04 | 23.9 | 0.05 | 1 (8%) | 0 (0%) | 0.3023 | 5 (1%) | 0.1423 | 5 (0.2%) | 0.0306 |
SERPINA7 | rs1804495 | 0.01 | 23.8 | 0.46 | 9 (69%) | 3 (10%) | 0.0002 | 179 (36%) | 0.0180 | 623 (25%) | 0.0010 |