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Table 1 Frequency of potential driver mutations (PDMs) in the selected genes, and their co-occurrence in carotid body tumor (CBT) samples

From: Exome analysis of carotid body tumor

Gene Frequency of samples with mutations, % Associations with mutations in the other genes
SDHD 13.5 RET, KMT2D, IDH1
IDH1 7.7 SDHB, SDHD, TP53BP1, TP53BP2, TP53I13
SDHB 7.7 IDH1, FGFR3, TP53I13, KMT2D
ARNT 5.8 BRAF, TP53BP1
SDHC 5.8 SDHC , SETD2,MEN1
KMT2D 5.8 SDHD, SDHB, FGFR3
TP53BP1 5.8 ARNT, BRAF, IDH1
TP53BP2 3.8 TP53BP2 , IDH1
TP53I13 3.8 IDH1, SDHB
RET 3.8 SDHD
KIF1B 3.8 BAP1
CDKN2A 1.9
BRAF 1.9 ARNT, TP53BP1
BRCA2 1.9 CSDE1
BAP1 1.9 KIF1B
CSDE1 1.9 BRCA2
SETD2 1.9 SDHC
MEN1 1.9 SDHC
FGFR3 1.9 SDHB, KMT2D
BRCA1 1.9
SDHA 1.9
  1. Genes which have two mutations in one sample are indicated with bold