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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Fig. 4

Venn diagrams of the differentially expressed genes of Nutlin-3 moderately insensitive cell lines versus sensitive cell lines after treatment by Nutlin-3 in two different dosages (5 μM and 30 μM) and in control. a Genes with increased expression; b Genes with decreased expression. Full LogFC computations for all three conditions can be found in Additional file 2: Table S1 (tab Nsen vs Sen)

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