Skip to main content
Fig. 6 | BMC Medical Genomics

Fig. 6

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Fig. 6

Visualization of canonical PI3K sub-pathway that leads to inhibition of p53 (PI3K ---Mdm2-−−/ p53). PI3K is represented on the diagram as the complex “p85:p110”. Yellow shadow around molecules represents the LogFC of the gene expression differences between Nutlin-3 insensitive and sensitive cell lines

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us