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Table 2 Genes differentially expressed (UP and DOWN) upon treatment by Nutlin-3 in insensitive and in sensitive cell lines

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Nutlin-3 Dosage (μM)

Sensitive

Insensitive

UP

DOWN

UP

DOWN

5

8

0

28

5

30

34

33

147

127