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Table 3 Table 3. Genes differentially expressed (Increased and Decreased) in Nutlin-3 insensitive cell lines as compared to the sensitive cell lines at baseline and under increasing dosage of Nutlin-3 stimulation.

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Nutlin-3 Dosage (μM) Increased Decreased Total
0 (Control) 257 366 623
5 297 377 674
30 258 368 626