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Table 5 Three chemical inhibitors used in this work for the validation of molecular targets

From: Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

#

cat №

Chemical name (Cayman)

Target(s)

I1

Cay70920–5

LY294002

PI3K

I2

Cay10005229–5

2,3-DCPE (hydrochloride)

Bcl-XL

I3

Cay10565–25

NVP-BEZ235

PI3K and mTOR