Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

Table 5 Three chemical inhibitors used in this work for the validation of molecular targets

#	cat №	Chemical name (Cayman)	Target(s)
I1	Cay70920–5	LY294002	PI3K
I2	Cay10005229–5	2,3-DCPE (hydrochloride)	Bcl-XL
I3	Cay10565–25	NVP-BEZ235	PI3K and mTOR

ISSN: 1755-8794