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Table 2 List of 31 CpG sites showing significant differences in methylation between centenarians and healthy controls

From: Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

Probe ID P Value FDR Δ β Gene Region Chromosome
Hypermethylated genes
 cg24724428 9.49E-08 2.94E-03 0.203271068 ELOVL2 TSS1500 6
 cg23448505 1.09E-04 6.99E-02 0.210419612 HKR1 5’UTR 19
 cg14166009 1.10E-04 7.04E-02 0.206571283 HKR1 TSS1500 19
 cg13687570 1.46E-04 7.97E-02 0.224156561 HKR1 TSS1500 19
 cg26734888 2.82E-04 1.08E-01 0.215848099 HKR1 TSS1500 19
 cg12948621 2.86E-04 1.09E-01 0.201660605 HKR1 TSS200 19
 cg24834889 9.41E-04 1.79E-01 0.229230299 HKR1 TSS200 19
 cg05280698 1.95E-03 2.32E-01 0.22951704 HKR1 TSS200 19
 cg11949518 2.54E-03 2.52E-01 0.227662305 RPTOR Body 17
Hypomethylated genes
 cg07839457 7.52E-08 2.94E-03 −0.283566443 NLRC5 TSS1500 16
 cg04233669 2.70E-07 4.49E-03 −0.210848478 LOC153328 Body 5
 cg00008629 4.19E-07 5.21E-03 −0.237495141 ROD1 5’UTR 9
 cg24892069 2.60E-05 2.07E-01 −0.205487552 NRP1 TSS1500 10
 cg01499623 4.50E-05 4.55E-02 −0.232050941 SMU1 Body 9
 cg22359828 5.49E-05 5.01E-02 −0.206320371 CACNA1E Body 1
 cg03930097 7.66E-05 5.82E-02 −0.201870989 HLA-DRA Body 6
 cg04329478 9.57E-05 6.52E-02 −0.259320244 LOC400696 TSS200 19
 cg17608381 1.24E-04 7.37E-02 −0.331606794 HLA-A Body 6
 cg04357717 3.55E-04 1.21E-01 −0.210909327 ZPLD1 Body 3
 cg11946459 3.56E-04 1.21E-01 −0.283888936 HLA-A Body 6
 cg13877915 8.02E-04 1.68E-01 −0.241392036 ZNF132 TSS200 19
 cg26856631 9.82E-04 1.81E-01 −0.409805022 LSM5 3’UTR 7
 cg25817503 1.20E-03 1.95E-01 −0.227151237 AFAP1 Body 4
 cg08309069 1.43E-03 2.07E-01 −0.249630086 HLA-C TSS1500 6
 cg08124030 2.23E-03 2.41E-01 −0.321896757 TM4SF1 1stExon 3
 cg05761882 2.59E-03 2.53E-01 −0.213920774 CAPN2 Body 1
 cg15295200 5.13E-03 3.14E-01 −0.381483294 NMNAT3 TSS1500 3
 cg25637655 5.97E-03 3.28E-01 −0.217322003 HLA-A Body 6
 cg03263197 6.62E-03 3.36E-01 −0.203535875 UBL4B TSS1500 1
 cg02746108 6.97E-03 3.40E-01 −0.225251292 AGAP1 Body 2
 cg05194426 8.66E-03 3.59E-01 −0.230652944 CYP2E1 Body 10