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Table 3 Analysis of significantly hypermethylated differentially methylated probes (DMPs)

From: Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians

GO ID Description P Value Genes
Biological process
 GO:0048002 antigen processing and presentation of peptide antigen 4.27E-04 HLA-A, HLA-C, HLA-DRA
 GO:0019882 antigen processing and presentation 3.70E-03 HLA-A, HLA-C, HLA-DRA
 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.86E-02 HLA-A, HLA-C
Cellular component
 GO:0042611 MHC protein complex 1.71E-03 HLA-A, HLA-C, HLA-DRA
 GO:0042612 MHC class I protein complex 3.02E-02 HLA-A, HLA-C
 GO:0005626 insoluble fraction 5.95E-02 ELOVL2, HLA-C, CYP2E1, CAPN2
 GO:0044459 plasma membrane part 7.76E-02 HLA-A, HLA-C, CACNA1E, TM4SF1, AFAP1, HLA-DRA
 GO:0005886 plasma membrane 8.86E-02 NRP1, HLA-A, HLA-C, CACNA1E, TM4SF1, CAPN2, AFAP1, HLA-DRA
 GO:0031224 intrinsic to membrane 8.97E-02 ZPLD1, NRP1, ELOVL2, HLA-A, HLA-C, CACNA1E, TM4SF1, LOC153328, CYP2E1, HLA-DRA
Molecular function
 GO:0032393 MHC class I receptor activity 2.07E-02 HLA-A, HLA-C
 GO:0032395 MHC class II receptor activity 2.31E-02 HLA-C, HLA-DRA