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Table 1 Fitted expression of macrophage subtype-specific markers

From: Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

Gene Subtype β0a βsubtype p-value Gene Subtype β0 βsubtype p-value
CCL2 M1 − 11.57 1.73 0.005 CCL17 M2a − 12.04 − 1.04 < 0.001
CCL3 M1 − 9.66 1.18 0.009 CCL18 M2a − 13.42 − 0.459 0.219
CCL5 M1 − 11.82 2.03 0.034 CCL22 M2a − 7.24 0.0164 0.904
CXCL10 M1 expressed in H5N1  6-h only CCL24 M2a − 13.58 − 1.19 0.066
CXCL11 M1 − 24.95 13.07 0.001 CXCR1 M2a not expressed
CXCL16 M1 − 8.47 0.0759 0.443 CXCR2 M2a not expressed
CXCL9 M1 − 13.76 2.25 0.027 IL1R2 M2a − 11.25 − 0.300 0.027
IL12A M1 − 13.98 0.576 0.150 CD163 M2a − 9.96 0.238 0.176
IL23A M1 − 13.64 0.835 0.148 FCER2 M2a − 12.21 − 1.28 0.003
IL8 M1 − 8.87 0.881 0.100 IL10 M2a/b/c − 11.86 0.379 0.035
CCR7 M1 − 11.97 0.367 0.351 ARG1 M2a/b/c − 14.54 − 0.289 0.652
TLR2 M1 − 9.74 0.288 0.028 IL1RN M2a/c − 7.34 0.677 0.002
TLR4 M1 − 8.28 0.488 < 0.001 MRC1 M2a/c − 12.23 − 0.869 0.182
  MRC2 M2a/c − 9.79 − 0.455 0.032
CCL1 M2b − 13.94 − 0.895 0.098
CCL16 M2c − 13.39 − 0.814 0.067
CCL18 M2c − 13.42 − 0.459 0.219
CXCL13 M2c − 10.44 − 0.739 < 0.001
TGFB1 M2c − 9.45 − 0.508 0.047
CCR2 M2c − 12.94 − 0.343 0.378
CD14 M2c − 8.83 − 0.592 0.003
SLAMF1 M2c − 11.22 − 0.166 0.251
  1. aβ0 indicates the intercept for the fitted linear model
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