A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

Table 4 Results of the linkage analyses

Trait	N	Chr.	SNP	LOD-2 SI Lower	LOD-2 SI Upper	Position (cM)	LOD_MAX
SL	1860	4	rs1032328	90,166,159	157,272,456	144.46	2.14
SL	1860	15	rs290370	88,026,435	102,212,431	112.3	1.92
SL	1860	20	rs204115	11,094,951	23,352,685	38.11	2.64
CV	1860	1	rs6619	12,296,232	53,396,842	59.63	2.40
CV	1860	6	rs2040431	72,253,060	117,799,468	108.31	2.17
12LS	1860	5	rs1442470	7,205,420	25,399,905	42.3	2.18
12LS	1860	20	rs466243	11,017,796	23,352,685	40.7	2.12
PC1	1860	11	rs1530354	33,896,047	78,743,080	65.21	2.01
PC1	1860	20	rs2077147	11,990,037	38,247,165	45.09	2.83
PC2	1860	6	rs1391503	87,511,828	105,402,837	99.69	2.09
PC2	1860	9	rs748530	8,378,662	25,788,723	40.22	2.35
PC2	1860	15	rs1562203	–	23,707,591	0	3.01
PC2	1860	22	rs138383	35,687,558	44,707,606	46.89	1.99

Model adjusted for age, sex, body-mass index, and height
SL Sokolow-Lyon, CV Cornell Voltage product, 12LS twelve-lead sum product, PC1 first principal component, PC2 second principal component, N sample size, Chr. chromosome, LOD-2 SI Lower position of lower boundary of support interval in base pairs, LOD-2 SI Upper position of upper boundary of support interval in base pairs, LOD_MAX LOD score at SNP

ISSN: 1755-8794