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Table 5 Top association signals from the microarray data under the LVH trait linkage peaks

From: A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

Outcome Region SNP MAF Gene P-value Q-value
SL 4q26 rs6839953 0.27 TRAM1L1 1.34 × 10−4 0.47
SL 15q26.2 rs11074275 0.48 MCTP2 4.27 × 10−4 0.79
SL 20p12.1 rs721243 0.19 ISM1 7.37 × 10−5 0.15
CV 1p35.1 rs16835131 0.06 SYNC 1.35 × 10−5 0.35
CV 6q15 rs10944412 0.27 RNGTT 4.60 × 10−5 0.93
12LS 5p15.2 rs2589661 0.10 ROPN1L 1.26 × 10− 4 0.46
12LS 20p11.23 rs6106235 0.18 C20orf26 1.69 × 10−5 0.09
PC1 11q12.2 rs1790325 0.04 FADS1 2.85 × 10−5 0.08
PC1 20p12.1 rs13036282 0.005 SPTLC3 2.30 × 10−4 0.63
PC2 6q16.3 rs1475922 0.06 GRIK2 1.64 × 10−4 0.94
PC2 9p24.1 rs10975939 0.003 KDM4C 4.67 × 10−4 1.00
PC2 15q11.2 rs8043191 0.03 CYFIP1 5.95 × 10−3 0.52
PC2 22q13.33 rs2688089 0.45 C22orf34 7.02 × 10−5 0.56
  1. SL Sokolow-Lyon, CV Cornell Voltage product, 12LS twelve-lead sum product, PC1 first principal component, PC2 second principal component, MAF minor allele frequency