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Table 6 P-values from EXAT, as compared to other methods, for identifying the significance of 19 pancreatic cancer-associated oncogenes

From: Exact association test for small size sequencing data

Gene name EXAT SKAT SKAT-O RC-SKAT Burden
PPP2R1A 0.046 0.012 0.012 0.001 0.047
AURKB 0.002 0.059 0.001 0.019 0.029
CYP2C19 0.006 0.099 0.027 0.016 0.032
KMT2D 0.002 0.082 0.013 0.227 0.027
KRAS 0.025 0.720 0.325 0.094 0.191
PIK3C2B 0.029 0.377 0.025 0.452 0.036
CDH5 0.016 0.056 0.006 0.351 0.012
MAPK1 0.036 0.018 0.018 0.018 0.110
FLT1 0.001 0.148 0.120 0.105 0.108
PIK3CB 0.036 0.183 0.274 0.183 0.395
NBN 0.037 0.218 0.330 0.130 0.671
MSH6 0.015 0.161 0.214 0.119 0.872
LCK 0.042 0.250 0.082 0.250 0.099
ARID2 0.015 0.189 0.277 0.155 0.404
ADAMTS20 0.026 0.511 0.289 0.658 0.176
LPP 0.013 0.359 0.277 0.011 0.196
KDM6A 0.016 0.332 0.016 0.481 0.024
GUCY1A2 0.012 0.398 0.023 0.408 0.031
THBS1 0.049 0.108 0.165 0.077 0.377