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Table 4 Number of significant genes at the Bonferroni-adjusted 0.05 significance level

From: WISARD: workbench for integrated superfast association studies for related datasets

Phenotype

WISARD

PedCMC

famVT

SKAT

cFARVAT-s

cFARVAT-b

cFARVAT-o

DPOF2575

4

2

0

1

0

1

F2575RAT

0

1

1

1

0

1

FEVPRE

1

0

1

0

0

0

FVCPST

4

1

2

3

2

3

RATIO

1

0

0

0

0

0

Phenotype

famSKAT

MONSTER

FREGAT

famBT

famFLM

FFBSKAT

MLR

DPOF2575

5

1

1

11

5

11

F2575RAT

0

0

0

4

0

4

FEVPRE

2

0

0

11

3

11

FVCPST

9

0

0

34

9

34

RATIO

0

0

0

0

0

0

  1. Rare variant association analyses of DPOF2575, F2575RAT, FEVPRE, FVCPST and RATIO were conducted with EOCOPD data. Upper and lower table display results from WISARD and other toolsets, respectively. Bolded numbers represent the number of identified genes from newly proposed methods