Table 7 miRNAs that are previously known to be associated with PD associated with non-PD-specific genes identified in our study
miRNAs from blood | mRNA targets associated with the miRNAs | miRNAs from substantia nigra | mRNA targets associated with the miRNAs |
|---|---|---|---|
hsa-let-7 g-5p | NCOA3 | hsa-let-7a-5p | SNAP23 |
hsa-let-7i-5p | IRS2 | hsa-let-7e-5p | SNAP23 |
hsa-miR-101-5p | TMX4 | hsa-miR-106a-5p | NIN |
hsa-miR-106a-5p | NCOA3 | hsa-miR-106b-5p | NIN |
hsa-miR-106b-5p | ABHD5, NCOA3 | hsa-miR-125a-5p | NIN |
hsa-miR-125a-5p | MAP2K7 | hsa-miR-17-5p | SNTB2 |
hsa-miR-132-3p | ATM | hsa-miR-182–5p | SNTB2 |
hsa-miR-132–5p | BCL2 | hsa-miR-20a-5p | NIN |
hsa-miR-143-3p | FAM102A | hsa-miR-23b-3p | NIN, SNTB2 |
hsa-miR-17-5p | ABHD5, NCOA3 | hsa-miR-25-3p | SNTB2 |
hsa-miR-181c-5p | NCOA3 | hsa-miR-302d-5p | SNTB2 |
hsa-miR-182–5p | BCL2 | hsa-miR-30a-5p | SNTB2 |
hsa-miR-18a-5p | ATM | hsa-miR-30e-5p | SNTB2 |
hsa-miR-20a-5p | ABHD5, NCOA3 | hsa-miR-93-5p | SNTB2 |
hsa-miR-212-3p | LRRFIP1 | hsa-miR-9-5p | SNTB2 |
hsa-miR-214-3p | FAM120A | ||
hsa-miR-23b-3p | BCL2 | ||
hsa-miR-25-3p | NCOA3 | ||
hsa-miR-27a-3p | ABCA1, FAM102A, FAM120A | ||
hsa-miR-27b-3p | NCOA3 | ||
hsa-miR-30e-5p | IRS2 | ||
hsa-miR-34a-5p | AKAP13, ATM, BCL2 | ||
hsa-miR-34c-5p | AKAP13 | ||
hsa-miR-363-3p | IRS2 | ||
hsa-miR-93-5p | ABCA1, ABHD5 |