Fig. 2From: Genome-wide association study identifies two loci influencing plasma neurofilament light levelsMean plasma NFL levels of different diagnostic groups and genotypes. Mean and standard errors of plasma NFL levels are shown for groups defined by baseline diagnosis and genotypes. P < 0.05 was considered statistically significant after examination with a multiple linear regression model using age, gender and the diagnosis as covariates. a The minor alleleofrs7943454 (T) showed association with higher plasma NFL levels in a dose-dependent effect in all diagnostic groups. b The minor allele of rs640476 (G) showed association with lower plasma NFL levels in a dose-dependent effect in all diagnostic groups except the MCI groupBack to article page