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Table 2 Top SNPs associated with plasma NFL levels (P values < 10− 5)

From: Genome-wide association study identifies two loci influencing plasma neurofilament light levels

CHR

SNP

MAF

Closest Gene

SNP Type/Location

P values

11

rs7943454

0.460

LUZP2

intron

1.39 × 10−6

5

rs640476

0.297

GABRB2

intergenic

6.71 × 10−6

  1. Abbreviations: CHR chromosome, LUZP2 leucine zipper protein 2, MAF minor allele frequency, SNP single nucleotide polymorphism, GABRB2 gamma-aminobutyric acid type A receptor beta2 subunit