Fig. 2
From: Calculating the statistical significance of rare variants causal for Mendelian and complex disorders
Population differences between the number of individuals mutated for a gene between populations. a Each data point in the histogram represents the proportion of individuals within a population who are heterozygous or homozygous for an uncommon (MAF < 5%) missense variant in a given gene. b The number of individuals carrying uncommon variants in a gene differs between populations. We plotted the variance of the count for each gene and colored high-variance genes to denote which population differed most from the mean