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Table 3 Allele and genotype frequencies of SNPs in CP patients with spastic tetraplegia and controls

From: Association of NOS1 gene polymorphisms with cerebral palsy in a Han Chinese population: a case-control study

Group

Allele frequency

P

OR (95% CI)

Genotype frequency

P

rs3782219

C

T

  

C/C

C/T

T/T

 

Case

255 (0.536)

221 (0.464)

0.006a

0.742

63 (0.265)

129 (0.542)

46 (0.193)

0.013

Control

774 (0.608)

498 (0.392)

(0.600~ 0.918)

235 (0.369)

304 (0.478)

97 (0.153)

rs2293054

A

G

  

A/A

A/G

G/G

 

Case

110 (0.231)

366 (0.769)

0.140

1.211

16 (0.067)

78 (0.328)

144 (0.605)

0.226

Control

253 (0.199)

1019 (0.801)

(0.939~ 1.560)

26 (0.041)

201 (0.316)

409 (0.643)

 

rs10774909

C

G

  

C/C

C/G

G/G

 

Case

328 (0.689)

148 (0.311)

0.695

1.047

106 (0.445)

116 (0.487)

16 (0.067)

0.159

Control

864 (0.679)

408 (0.321)

(0.834~ 1.313)

294 (0.462)

276 (0.434)

66 (0.104)

 

rs3741475

A

G

  

A/A

A/G

G/G

 

Case

108 (0.227)

368 (0.773)

0.079

0.801

8 (0.034)

92 (0.387)

138 (0.580)

0.043

Control

341 (0.268)

931 (0.732)

(0.625~ 1.027)

52 (0.082)

237 (0.373)

347 (0.546)

 

rs2682826

A

G

  

A/A

A/G

G/G

 

Case

109 (0.229)

367 (0.771)

0.142

0.831

8 (0.034)

93 (0.391)

137 (0.576)

0.042

Control

335 (0.263)

937 (0.737)

(0.649~ 1.064)

52 (0.082)

231 (0.363)

353 (0.555)

 
  1. a After the SNPSpD correction, p = 0.023