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Table 5 Allele and genotype frequencies of SNPs in CP patients with neonatal encephalopathy and controls

From: Association of NOS1 gene polymorphisms with cerebral palsy in a Han Chinese population: a case-control study

Group

Allele frequency

P

OR (95% CI)

Genotype frequency

P

rs3782219

C

T

  

C/C

C/T

T/T

 

Case

300 (0.575)

222 (0.425)

0.185

0.869

82 (0.314)

136 (0.521)

43 (0.165)

0.289

Control

774 (0.608)

498 (0.392)

 

(0.707~ 1.069)

235 (0.369)

304 (0.478)

97 (0.153)

 

rs2293054

A

G

  

A/A

A/G

G/G

 

Case

122 (0.234)

400 (0.766)

0.100

1.228

15 (0.057)

92 (0.352)

154 (0.590)

0.256

Control

253 (0.199)

1019 (0.801)

 

(0.961~ 1.560)

26 (0.041)

201 (0.316)

409 (0.643)

 

rs10774909

C

G

  

C/C

C/G

G/G

 

Case

343 (0.657)

179 (0.343)

0.364

0.905

98 (0.375)

147 (0.563)

16 (0.061)

0.001 a

Control

864 (0.679)

408 (0.321)

 

(0.729~ 1.123)

294 (0.462)

276 (0.434)

66 (0.104)

 

rs3741475

A

G

  

A/A

A/G

G/G

 

Case

145 (0.278)

377 (0.722)

0.675

1.050

10 (0.038)

125 (0.479)

126 (0.483)

0.003 b

Control

341 (0.268)

931 (0.732)

 

(0.836~ 1.319)

52 (0.082)

237 (0.373)

347 (0.546)

 

rs2682826

A

G

  

A/A

A/G

G/G

 

Case

145 (0.278)

377 (0.722)

0.531

1.076

9 (0.034)

127 (0.487)

125 (0.479)

0.0005 c

Control

335 (0.263)

937 (0.737)

 

(0.856~ 1.352)

52 (0.082)

231 (0.363)

353 (0.555)

 
  1. aAfter the SNPSpD correction, p = 0.004; bAfter the SNPSpD correction, p = 0.012; cAfter the SNPSpD correction, p = 0.002