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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis

Fig. 1

Overview of the study design. A total of 16 patients with GCA had serial blood tests to investigate the gene expression profiles of T lymphocytes over the course of their disease. CD4+ and CD8+ cells were positively selected through magnetic assisted cell sorting (MACS). RNA was extracted for subsequent RNA sequencing. The expression profiles of patients were compared to that of 16 age-matched controls. In addition to differential gene expression analysis and longitudinal transcript analysis, clinical phenotype regression analysis was performed to investigate genes predictive of acute disease and prognosis

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BMC Medical Genomics

ISSN: 1755-8794

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