Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women

BMC Medical Genomics

Table 2 Association of previously reported GDM and T2D loci from Indian population based studies with risk of GDM according to both criteria

Genotype	EA	Chr	Gene/nearest gene	Location	OR_WHO1999	lower CI	upper CI	p_who1999	OR_WHO2013	lower CI	upper CI	p_who2013	n
rs998451	A	2	TMEM163	intron	0.987	0.795	1.224	0.902	0.959	0.843	1.09	0.518	3882
rs1799999	A	7	PPP1R3A	missense	0.862	0.728	1.02	0.083	0.997	0.905	1.098	0.953	3890
rs689	A	11	INS	5’UTR	1.077	0.879	1.319	0.474	1.033	0.914	1.167	0.603	3903
rs9552911	A	13	SGCG	intron	1.057	0.83	1.347	0.653	1.017	0.875	1.183	0.824	3890
rs4812829	A	20	HNF4A	intron	1.04	0.871	1.24	0.667	0.988	0.89	1.096	0.814	3801
rs7178572	G	15	HMG20A	intron	0.988	0.832	1.173	0.891	1.017	0.921	1.122	0.743	3541
rs7756992	G	6	CDKAL 1	intron	0.91	0.75	1.1	0.34	0.97	0.87	1.08	0.64	3686
rs7754840	C	6	CDKAL1	intron	0.87	0.72	1.06	0.17	0.96	0.86	1.07	0.51	3721

EA effect allele, OR_WHO1999 odds ratio based on WHO1999 criteria, OR_WHO2013 Odds ratio based on WHO2013 criteria, CI confidence interval

ISSN: 1755-8794