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Table 3 Association of previously reported GDM loci with risk of GDM according to both criteria

From: Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women

SNP EA Chr Gene/nearest gene Location WHO 1999 WHO 2013 n
OR CI(lower) CI(upper) p-value OR CI(lower) CI(upper) p-value
rs9939609 A 16 FTO intron 1.04 0.86 1.26 0.67 0.98 0.88 1.10 0.83 3120
rs2796441 G 9 TLE 1 intergenic 0.99 0.84 1.16 0.92 1.07 0.97 1.17 0.15 3905
rs560887 C 2 G6PC2/ABCB11 intron 1.18 0.92 1.52 0.19 1.11 0.96 1.28 0.13 3910
rs11708067 A 3 ADCY5 intron 0.98 0.81 1.18 0.86 0.88 0.79 0.99 0.037 3877
rs1111875 C 10 HHEX intergenic 0.90 0.77 1.06 0.22 1.05 0.96 1.16 0.24 3901
rs10811661 T 9 CDKN2A/2B intergenic 0.99 0.77 1.26 0.93 1.08 0.94 1.25 0.23 3890
rs4402960 T 3 IGF2BP2 intron 1.02 0.87 1.20 0.77 0.95 0.86 1.04 0.29 3750
rs13266634 C 8 SLC30A8 coding-missense 0.96 0.79 1.17 0.75 0.97 0.87 1.08 0.61 3898
rs7903146 T 10 TCF7L2 Intronic/promoter 1.13 0.95 1.35 0.14 1.01 0.916 1.12 0.76 3543
rs10830963 G 11 MTNR1B intron 0.89 0.75 1.05 0.20 0.98 0.89 1.08 0.69 3714
rs1801282 C 3 PPARG Coding-missense 0.86 0.89 1.12 0.22 0.99 0.93 1.08 0.21 3652
rs10010131 G 4 WFS1 intron 1.13 0.95 1.36 0.16 0.99 0.90 1.10 0.99 3843
rs5219 T 11 KCNJ11 coding-missense 1.21 1.03 1.42 0.019 1.00 0.90 1.10 0.99 3595
  1. EA effect allele, OR_WHO1999 odds ratio based on WHO1999 criteria, OR_WHO2013 Odds ratio based on WHO2013 criteria, CI confidence interval
  2. significant p values where p < 0.05 are indicated in bold