Table 4 APOC3 R19X frequency, by population
Population | Sample size | Carriers identified (Overall allele frequency) | Allele frequency in European-descent populations | PubMed ID or website |
|---|---|---|---|---|
European American adults with very low triglyceride levels | 184 | 2 (0.55%) | 0.55% | - (present study) |
Pennsylvania Amish | 2503 | 140 (5.6%) | 5.6% | 19074352 |
Greek isolate | 1219 | 48 (1.9%) | 1.9% | 24343240 |
Greek isolate | 1087 | 34 (1.42%) | 1.42% | 27146844 |
Americans regardless of health status | 19,613 | 31 (0.08%) | 0.20% | 25363704 |
Exome Aggregation Consortium (ExAC) | 60,103 | 83 (0.07%) | 0.046% | 27535533 (http://exac.broadinstitute.org/ accessed May 2017) |
National Heart, Lung, and Blood Institute (NHLBI) Grand Opportunity (GO) Exome Sequencing Project (ESP) | 6495 | 3 (0.02%) | 0.035% | 24941081 (http://evs.gs.washington.edu/EVS/ accessed June 2015) |
Ohio and Indiana Amish | 1113 | 0 (−) | – | 25363704 |
1000 Genomes Project | 2500 | 0 (−) | – | (http://useast.ensembl.org/index.html accessed June 2015) |
European Americans from Baltimore | 214 | 0 (−) | – | 19074352 |