Skip to main content

Advertisement

Table 4 APOC3 R19X frequency, by population

From: Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels

Population Sample size Carriers identified (Overall allele frequency) Allele frequency in European-descent populations PubMed ID or website
European American adults with very low triglyceride levels 184 2 (0.55%) 0.55% - (present study)
Pennsylvania Amish 2503 140 (5.6%) 5.6% 19074352
Greek isolate 1219 48 (1.9%) 1.9% 24343240
Greek isolate 1087 34 (1.42%) 1.42% 27146844
Americans regardless of health status 19,613 31 (0.08%) 0.20% 25363704
Exome Aggregation Consortium (ExAC) 60,103 83 (0.07%) 0.046% 27535533 (http://exac.broadinstitute.org/ accessed May 2017)
National Heart, Lung, and Blood Institute (NHLBI) Grand Opportunity (GO) Exome Sequencing Project (ESP) 6495 3 (0.02%) 0.035% 24941081 (http://evs.gs.washington.edu/EVS/ accessed June 2015)
Ohio and Indiana Amish 1113 0 (−) 25363704
1000 Genomes Project 2500 0 (−) (http://useast.ensembl.org/index.html accessed June 2015)
European Americans from Baltimore 214 0 (−) 19074352