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Table 1 Key known mutations of oncogenic genes detected by PanMutsRx

From: Indel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicine

 

Known

Detected

Sensitivity

BRAF V600E

1

1

1.00

CTNNB1 D32G

1

1

1.00

EGFR micro deletion

7

6 (7)

0.86 (1)a

EGFR SNV

14

13 (14)

0.93 (1)

KRAS SNV

14

14

1.00

MET SNV

1

1

1.00

NRAS SNV

3

3

1.00

  1. aNumbers in parenthesis are from GSNAP alignment