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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records

Fig. 2

Manhattan plot of EAGLE BioVU primary open-angle glaucoma Metabochip-wide tests of association in African Americans. Logistic regression assuming an additive genetic model was performed for 138 cases and 1376 controls adjusted by age, sex, principal components, and median diastolic blood pressure. P-values [(−log10) on the y-axis] for each test of association are plotted by chromosome (x-axis). The blue line depicts a suggestive significance threshold of p < 5.0 × 10− 4

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