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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Progression-specific genes identified in microdissected formalin-fixed and paraffin-embedded tissue containing matched ductal carcinoma in situ and invasive ductal breast cancers

Fig. 4

Independent validation of differential expression of the gene set in pDCIS and DCIS/IBC-tumours by qPCR. Expression of MMP11 increases significantly from pDCIS to DCIS of DCIS/IBC mixed tumours and IBC (P < 0.05) and COL10A1 increases significantly from pDCIS to DCIS of DCIS/IBC mixed tumours (P < 0.05). Differences in expression of the remaining genes are not significant (n.s.). PCR values are normalized to GAPDH, ACTB and YWHAZ

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