Table 2  Count of prioritized disease pairs by eQTL RNA overlap for each tissue
Tissue of eQTL associations | INPUT | OUTPUT | |||
|---|---|---|---|---|---|
Distinct eQTL SNPs | Distinct eQTL RNAs | Distinct SNP-RNA associations | Distinct diseases | Prioritized disease pairs (FDR < 5%) | |
Adipose subcutaneous | 620 | 489 | 2400 | 127 | 1581 |
Artery aorta | 337 | 200 | 1264 | 96 | 1198 |
Artery tibial | 492 | 365 | 1898 | 125 | 1331 |
Blood | 270 | 117 | 1388 | 77 | 1191 |
Brain | 188 | 50 | 554 | 67 | 448 |
Breast mammary tissue | 238 | 83 | 987 | 80 | 970 |
Cells transformed fibroblasts | 541 | 417 | 1485 | 123 | 799 |
Colon transverse | 231 | 95 | 810 | 80 | 748 |
Esophagus mucosa | 518 | 398 | 1927 | 126 | 1462 |
Esophagus muscularis | 560 | 421 | 1856 | 135 | 1366 |
Heart atrial appendage | 218 | 55 | 867 | 71 | 674 |
Heart left ventricle | 378 | 199 | 1283 | 104 | 1201 |
Lung | 154 | 138 | 416 | 68 | 45 |
Muscle skeletal | 551 | 408 | 2240 | 130 | 1617 |
Nerve tibial | 748 | 627 | 2497 | 134 | 1536 |
Pancreas | 279 | 126 | 843 | 85 | 753 |
Skin | 806 | 667 | 2669 | 155 | 1775 |
Stomach | 202 | 64 | 779 | 68 | 676 |
Thyroid | 857 | 793 | 2759 | 145 | 1484 |
Total (union of sets) | 1721 | 2644 | 8033 | 188 | 2043 |