CRlncRNA: a manually curated database of cancer-related long non-coding RNAs with experimental proof of functions on clinicopathological and molecular features

Table 1 Comparison of CRlncRNA with other cancer-related lncRNA databases

Database	lncRNA number	Basic data requirement	lncRNA sequence	Expression profile	Gene interaction	Cancer hallmarks	Clinical parameters
Lnc2Cancer	666	Expression^a	×	×	×	×	×
lnCaNet	9641	Expression^b	√	√	√	×	×
lncRNADisease	2478	Prediction^c	√	×	√	×	×
Lnc2Catlas	27,670	None^d	√	√	√	×	×
TANRIC	12,727	None^e	×	√	√	×	√
CRlncRNA	355	Functional^f	√	√	√	√	√

^aDifferential expression between cancer and normal samples
^bCo-expression with cancer-related protein-coding genes
^cMore than half of the collected lncRNAs are predicted base on its genomic context
^dAll lncRNAs from GENCODE database
^eAll intergenic lncRNAs from GENCODE database
^fLow-throughput functional experiments

ISSN: 1755-8794