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Fig. 14 | BMC Medical Genomics

Fig. 14

From: “Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy

Fig. 14

JASPAR prediction analysis. Legend: Figure shows the 5’-GCG(T/G)GGGCG-3′(EGR-site DNA sequence) and the ECHS1:rs10466126 (G/G) locus. The arrow indicates the ECHS1:rs10466126 (G/G) locus. Shown in these figures are a sequence logo, a count matrix, and hits/bp statistics. It is a graphical representation of the matrix model, based on the information content. The information content of a matrix column ranges from 0 (no base preference) and 2 (only one base used). The sequence logo is a barplot showing the total information content at each position. Bars are replaced by stacked letters (A,C,G,T), which are sized and sorted relative to their occurrence. The count matrix is the underlying model showing the DNA pattern. The numbers in cells indicate the number of sequences having base x in column y [23]

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