Table 1 Candidate driver genes positively selected (p-value ≤0.01) by each permutation model and their percentage (in brackets) of all genes tested for breast and lung cancer data
Permutation model | CADD | DANN | Fathmm-MKL coding | Fathmm-MKL noncoding | MetaLR | SPIDEX | VEST3 | Unique genes | Total genes |
|---|---|---|---|---|---|---|---|---|---|
Breast | 263 (1.3) | 158 (0.8) | 178 (0.9) | 184 (0.9) | 174 (0.9) | 178 (0.9) | 171 (0.9) | 942 (4.7) | 19,835 |
Lung | 121 (0.6) | 142 (0.7) | 138 (0.7) | 149 (0.7) | 178 (0.9) | 171 (0.9) | 164 (0.8) | 796 (4.0) | 20,047 |