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Table 1 Summary of the integrated regulatory relationships among miRNAs, TFs and genes

From: Network-based identification of critical regulators as putative drivers of human cleft lip

Relationship Number of pairs Number of miRNAs Number of genes Number of TFs Methoda
miRNA-gene 77 9 37 / A
miRNA-TF 21 8 / 12 A
TF-gene 671 / 126 27 B
TF-miRNA 76 17 / 22 B
Total 845 18 127 27  
  1. aIn the Method column, (A) regulation relationships were supported by at least two of these databases: TargetScan, miRanda, PITA and miRTarBase; (B) TRANSFAC Match™ method was used for identification of TF-target relationship