Table 2 List of binary phenotypes
Short name | Category | Full description | Number of “yes” | Number of samples | Frequency of “yes” (%) |
|---|---|---|---|---|---|
Prevalent Phenotypes | |||||
Aging | Cognitive Status: Normal: defined as cogscore> 4, Impaired: defined as cogscore <=4 | 744 | 6195 | 12.01 | |
Falls [28] | Aging | Self-reported fall in the past year | 1166 | 7704 | 15.13 |
CVD related | Atrial Fibrillation (self-report or ECG evidence) | 573 | 7526 | 7.61 | |
CAD [31] | CVD related | History of Heart Disease (self-reported MI, CABG, bypass, angioplasty, or stenting OR evidence of MI via ECG | 1186 | 7582 | 15.64 |
DVT [32] | CVD related | Self-reported deep vein thrombosis | 371 | 7699 | 4.82 |
CVD related | Hypertensive if SBP > =140 or DBP > =90 or self-reported current medication use to control blood pressure | 5622 | 7714 | 72.88 | |
Dyslipidemia [35] | CVD related | Dyslipidemia: if TC > =240 or LDL > =160 or HDL < =40 or on medication | 4171 | 7604 | 54.85 |
MI_SR [31] | CVD related | History of Myocardial Infarction (MI) (self-reported MI OR evidence of MI via ECG | 891 | 7588 | 11.74 |
PAD_amputation [36] | CVD related | History of leg amputation | 40 | 7725 | 0.52 |
PAD_surgery [36] | CVD related | Self-reported procedure to fix the arteries in legs | 162 | 7709 | 2.1 |
CVD related | Participant reported stroke at baseline | 597 | 7701 | 7.75 | |
CVD related | Presence of stroke symptoms at baseline | 1632 | 7134 | 22.88 | |
CVD related | Participant reported Transient ischemic attack at baseline | 257 | 7102 | 3.62 | |
Diabetes [41] | Diabetes related | Diabetic if fasting glucose> = 126/non-fasting glucose> = 200 or pills or insulin | 2335 | 7639 | 30.57 |
Cancer [42] | Other | Have you ever been diagnosed with cancer | 526 | 4895 | 10.75 |
Orthopnea [29] | Other | Require more than one pillow to sleep at night | 1076 | 7702 | 13.97 |
Dialysis [43] | Renal | Self-reported dialysis | 45 | 7670 | 0.59 |
KidneyFailure [43] | Renal | Self-reported kidney failure | 164 | 7670 | 2.14 |
Incident Phenotypes | |||||
CHD [44] | CVD related | Incidence of coronary heart disease until 2012 | 436 | 7726 | 5.64 |
MI [44] | CVD related | Incidence of myocardial infarction until 2012 | 284 | 7726 | 3.68 |
Stroke [45] | CVD related | Incidence of Stroke until 20,150,401 | 287 | 7726 | 3.71 |
Death [46] | Other | Incidence of Death until 20,150,401 | 1494 | 7726 | 19.34 |
Other | Incidence of infection | 548 | 7726 | 7.09 | |
Other | Incidence of sepsis | 307 | 7726 | 3.97 | |
Other | Incidence of severe sepsis | 243 | 7726 | 3.15 | |
ESRD [49] | Renal | Incidence of end stage renal disease until 2012 | 238 | 7726 | 3.08 |