Skip to main content

Table 3 The list of continuous phenotypes of this study

From: A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study

Short name Category Full description Data transformation Number of samples Mean Standard deviation
CogScore [26, 27] Aging Computed cognitive score   6195 5.45 0.85
Falls_number [28] Aging Number of times fallen in the past year log10(x + 1) 1182 0.42 0.2
MCS [50] Aging The mental component of the short-form 12 health survey: Mental   7352 53.46 9.02
BMI [51] Body size Body Mass Index - kg/m2   7657 30.84 6.73
Height [51] Body size Height   7702 66.4 3.88
Waist_cm [51] Body size Waist circumference (cm)   7673 98.43 15.42
Weight_kg [51] Body size Weight (kg)   7694 87.99 20.54
ARICStroke CVD related ARIC Stroke Risk Score: 10 Year Probability of Ischemic Scroke (%) log10 6791 0.83 0.47
Cholest [52] CVD related Total Cholesterol (mg/dL)   7676 193.1 40.9
Crp [53] CVD related C reactive protein (mg/L) log10 7597 0.46 0.52
DBP [54, 55] CVD related Diastolic blood pressure - average of two measures (mmHg)   7703 78.58 10.11
Fram_CHD_score [56] CVD related Framingham CHD Hard Event Risk Score: Risk of Coronary Death or MI over 10 Years (among those free of CHD at baseline) log10 6381 0.86 0.4
Fram_stroke_score [57] CVD related Framingham Stroke Risk Score: 10 Year Probability of Stroke (%) (among those who self-reported never having a stroke at baseline) log10 6694 0.88 0.39
Hdl [52] CVD related HDL Cholesterol (mg/dL)   7622 53.46 15.9
Heartrate [58] CVD related Heart rate (beats per minute)   7627 68.48 11.95
Ideal7 [59] CVD related American Heart Association Life simple seven, total number of ideal for each of the seven   7726 2.12 1.08
Ldl [52] CVD related LDL Cholesterol (mg/dL)   7566 116.81 36.42
SBP [54, 55] CVD related Systolic blood pressure - average of two measures (mmHg)   7703 131.41 17.29
SLFS [60] CVD related Family risk score for stroke   4293 −0.48 0.33
Stroke_Sym_Number [39, 40] CVD related Number of stroke symptoms   7134 0.39 0.87
Trigly [52] CVD related Triglycerides (mg/dL) log10 7673 2.01 0.2
Glucose [41] Diatetes related Glucose (mg/dL from labs formerly from fromVermont) sqrt 7676 10.38 1.78
Insulin [41] Diatetes related Endogenous Insulin uU/mL log10 5619 1.09 0.35
CESD [61] Other Center for Epidemiologic Studies Depression Scale   7670 1.39 2.21
DASH_Score [62] Other DASH style diet score   4592 23.11 4.25
Diet7 [59] Other Life simple seven, diet score   4592 1.17 0.37
Education [63] Other 1 = ‘Less than high school’; 2 = ‘High school graduate’; 3 = ‘Some college’; 4 = ‘College graduate and above’; missing = − 9.   7718 2.57 1.08
Income [63] Other Income   6763 5.7 2.13
MedDietScore [64] Other Mediterranean diet score   4483 4.43 1.64
PA7 [59] Other Life simple seven, physical activity   7618 1.89 0.79
PCS [50] Other PCS-12: SF-12 Physical square root 7325 4.55 1.1
Smoke7 Other Life simple seven, smoking   7726 2.63 0.76
TV [65] Other watching TV time. 0 = ‘None’; 1 = ‘1–6 h/wk’; 2 = ‘1 h/day’; 3 = ‘2 h/day’; 4 = ‘3 h/day’; 5 = ‘4+ hrs/day’; missing = − 9.   5408 3.81 1.39
ACR [66] Rental Urinary Albumin/Creatinine ratio (mg/g) log10 7421 1.09 0.62
Albumin_urine [66] Rental Urinary albumin (mg/L) log10 7423 1.2 0.63
BUN [66] Rental Blood-urea-nitrogen (mg/dL) log10 5472 1.18 0.16
Creatinine_serum [67] Rental IDMS Calibrated Creatinine (mg/dL) log10(x + 1) 7674 0.29 0.09
Creatinine_urine [66] Rental Urinary creatinine (mg/dL)   7437 152.1 84.59
Cysc [67] Rental Cystatin C (mg/L) log10 7597 0 0.14
EGFR_CKDEPI [68] Rental estimated GFR from the CKD-Epi equation   7674 87.52 23.67
EGFR_MDRD [68] Rental Glomerular Filtration Rate (mL/min/1.73 square meters) using IDMS calibrated creatinine and MDRD equation   7674 89.36 27.15