Table 3 The list of continuous phenotypes of this study
Short name | Category | Full description | Data transformation | Number of samples | Mean | Standard deviation |
|---|---|---|---|---|---|---|
Aging | Computed cognitive score | Â | 6195 | 5.45 | 0.85 | |
Falls_number [28] | Aging | Number of times fallen in the past year | log10(x + 1) | 1182 | 0.42 | 0.2 |
MCS [50] | Aging | The mental component of the short-form 12 health survey: Mental | Â | 7352 | 53.46 | 9.02 |
BMI [51] | Body size | Body Mass Index - kg/m2 | Â | 7657 | 30.84 | 6.73 |
Height [51] | Body size | Height | Â | 7702 | 66.4 | 3.88 |
Waist_cm [51] | Body size | Waist circumference (cm) | Â | 7673 | 98.43 | 15.42 |
Weight_kg [51] | Body size | Weight (kg) | Â | 7694 | 87.99 | 20.54 |
ARICStroke | CVD related | ARIC Stroke Risk Score: 10 Year Probability of Ischemic Scroke (%) | log10 | 6791 | 0.83 | 0.47 |
Cholest [52] | CVD related | Total Cholesterol (mg/dL) | Â | 7676 | 193.1 | 40.9 |
Crp [53] | CVD related | C reactive protein (mg/L) | log10 | 7597 | 0.46 | 0.52 |
CVD related | Diastolic blood pressure - average of two measures (mmHg) | Â | 7703 | 78.58 | 10.11 | |
Fram_CHD_score [56] | CVD related | Framingham CHD Hard Event Risk Score: Risk of Coronary Death or MI over 10 Years (among those free of CHD at baseline) | log10 | 6381 | 0.86 | 0.4 |
Fram_stroke_score [57] | CVD related | Framingham Stroke Risk Score: 10 Year Probability of Stroke (%) (among those who self-reported never having a stroke at baseline) | log10 | 6694 | 0.88 | 0.39 |
Hdl [52] | CVD related | HDL Cholesterol (mg/dL) | Â | 7622 | 53.46 | 15.9 |
Heartrate [58] | CVD related | Heart rate (beats per minute) | Â | 7627 | 68.48 | 11.95 |
Ideal7 [59] | CVD related | American Heart Association Life simple seven, total number of ideal for each of the seven | Â | 7726 | 2.12 | 1.08 |
Ldl [52] | CVD related | LDL Cholesterol (mg/dL) | Â | 7566 | 116.81 | 36.42 |
CVD related | Systolic blood pressure - average of two measures (mmHg) | Â | 7703 | 131.41 | 17.29 | |
SLFS [60] | CVD related | Family risk score for stroke |  | 4293 | −0.48 | 0.33 |
CVD related | Number of stroke symptoms | Â | 7134 | 0.39 | 0.87 | |
Trigly [52] | CVD related | Triglycerides (mg/dL) | log10 | 7673 | 2.01 | 0.2 |
Glucose [41] | Diatetes related | Glucose (mg/dL from labs formerly from fromVermont) | sqrt | 7676 | 10.38 | 1.78 |
Insulin [41] | Diatetes related | Endogenous Insulin uU/mL | log10 | 5619 | 1.09 | 0.35 |
CESD [61] | Other | Center for Epidemiologic Studies Depression Scale | Â | 7670 | 1.39 | 2.21 |
DASH_Score [62] | Other | DASH style diet score | Â | 4592 | 23.11 | 4.25 |
Diet7 [59] | Other | Life simple seven, diet score | Â | 4592 | 1.17 | 0.37 |
Education [63] | Other | 1 = ‘Less than high school’; 2 = ‘High school graduate’; 3 = ‘Some college’; 4 = ‘College graduate and above’; missing = − 9. |  | 7718 | 2.57 | 1.08 |
Income [63] | Other | Income | Â | 6763 | 5.7 | 2.13 |
MedDietScore [64] | Other | Mediterranean diet score | Â | 4483 | 4.43 | 1.64 |
PA7 [59] | Other | Life simple seven, physical activity | Â | 7618 | 1.89 | 0.79 |
PCS [50] | Other | PCS-12: SF-12 Physical | square root | 7325 | 4.55 | 1.1 |
Smoke7 | Other | Life simple seven, smoking | Â | 7726 | 2.63 | 0.76 |
TV [65] | Other | watching TV time. 0 = ‘None’; 1 = ‘1–6 h/wk’; 2 = ‘1 h/day’; 3 = ‘2 h/day’; 4 = ‘3 h/day’; 5 = ‘4+ hrs/day’; missing = − 9. |  | 5408 | 3.81 | 1.39 |
ACR [66] | Rental | Urinary Albumin/Creatinine ratio (mg/g) | log10 | 7421 | 1.09 | 0.62 |
Albumin_urine [66] | Rental | Urinary albumin (mg/L) | log10 | 7423 | 1.2 | 0.63 |
BUN [66] | Rental | Blood-urea-nitrogen (mg/dL) | log10 | 5472 | 1.18 | 0.16 |
Creatinine_serum [67] | Rental | IDMS Calibrated Creatinine (mg/dL) | log10(x + 1) | 7674 | 0.29 | 0.09 |
Creatinine_urine [66] | Rental | Urinary creatinine (mg/dL) | Â | 7437 | 152.1 | 84.59 |
Cysc [67] | Rental | Cystatin C (mg/L) | log10 | 7597 | 0 | 0.14 |
EGFR_CKDEPI [68] | Rental | estimated GFR from the CKD-Epi equation | Â | 7674 | 87.52 | 23.67 |
EGFR_MDRD [68] | Rental | Glomerular Filtration Rate (mL/min/1.73 square meters) using IDMS calibrated creatinine and MDRD equation | Â | 7674 | 89.36 | 27.15 |