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Table 1 Demographic and clinical characteristics of study participants

From: Comparison of DNA methylation profiles associated with spontaneous preterm birth in placenta and cord blood

 

sPTB (N = 32)

Term Birth (N = 16)

p-value

Mother

 Maternal age (years), mean (SD)

27.16 (4.14)

27.19 (3.90)

0.98

 Pre-pregnancy BMI, mean (SD)

20.06 (2.22)

18.80 (1.13)

0.04

 College or above education, N (%)

17 (53.10)

7 (43.80)

0.54

 Family income > ¥3000/month, N (%)

17 (53.10)

9 (56.30)

0.84

 Primiparity, N (%)

28 (87.50)

13 (81.30)

0.67

 Passive smoking, N (%)

22 (68.80)

8 (50.00)

0.21

 Alcohol use, N (%)

1 (3.10)

2 (12.50)

0.25

Placenta

 Placental surface area (cm2), mean (SD)a

260.41 (59.17)

286.43 (41.91)

0.12

 Placenta thickness (cm), mean (SD)

2.19 (0.47)

2.34 (0.47)

0.29

Newborn

 Gestational age (weeks), mean (SD)

35.09 (1.35)

39.63 (1.09)

< 0.001

 Gender (male), N (%)

59.40% (19/32)

56.30% (9/16)

0.84

 Birth weight (gram), mean (SD)

2436.53 (461.48)

2999.38 (268.28)

< 0.001

 Birth length (cm), mean (SD)

46.50 (2.70)

49.44 (1.63)

< 0.001

 Head circumference (cm), mean (SD)

31.13 (1.31)

32.38 (1.31)

0.003

  1. a The placental surface area was calculated using the formula for the area of ellipse: major axis × minor axis × π/4