Skip to main content
Fig. 1 | BMC Medical Genomics

Fig. 1

From: Chromosome (re)positioning in spermatozoa of fathers and sons – carriers of reciprocal chromosome translocation (RCT)

Fig. 1

A graphical model of the linear and radial measurement techniques of centromere localization within the sperm cell nucleus. a Linear positioning: frequency of FISH signals counted in 3 equal parts of the nucleus, delineated along the long ‘L’ axis: ‘t’ – near the tail, ‘m’ – middle, and ‘a’ – near the acrosome. b Radial positioning: centromere localization – central (deep inside the nucleus) or peripheral (close to the sperm nuclear membrane), according to normalized values depicted in a coordinate system: D/L ± SE for OX axis and H/L ± SE for OY axis, where L and l – lengths of the long and short axes of the sperm nucleus; D and H – distances from the FISH signal (green point) to the tail attachment point and to the long axis; ellipse – potential mirror image of centromere localization. c Schematically marked chromocenter areas (groups of centromeres) with their mirror image (grey area). Radial positioning was originally determined by Zalenskaya and Zalensky [52]

Back to article page