Chromosome
| |
T1
|
T2
|
T3
|
T4
|
T5
|
T6
|
T7
|
T8
|
T9
|
T10
|
T11
|
T12
|
T13
|
Control mean value [n = 8]
|
---|
t(1;11)
|
t(2;8)
|
t(2;10)
|
t(3;9)
|
t(4;10)
|
t(4;18)
|
t(6;14)
|
t(7;18)
|
t(11;13)
|
t(4;5) father
|
t(4;5) son
|
t(7;10) father
|
t(7;10) son
|
---|
4
|
D/L
|
0.547↑↑
|
0.507
|
0.498
|
0.521↑
|
0.505
|
0.519↑
|
0.557↑↑
|
0.500
|
0.491
|
0.632↑↑b
|
0.604↑↑b
|
0.578↑↑
|
0.561↑↑
|
0.498
|
se
|
0.015
|
0.008
|
0.008
|
0.008
|
0.008
|
0.008
|
0.009
|
0.001
|
0,010
|
0.009
|
0.008
|
0,012
|
0.008
|
0.008
|
H/L
|
0.151↓
|
0.171
|
0.194↑↑
|
0.186
|
0.169
|
0.166
|
0.183
|
0.153↓↓
|
0.172
|
0.179
|
0.175
|
0.177
|
0.187
|
0.175
|
se
|
0.005
|
0.004
|
0.003
|
0.003
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
7
|
D/L
|
0.590↑↑
|
0.533
|
0.518
|
0.549
|
0.539
|
0.521
|
0.554↑
|
0.502↓
|
0.538
|
0.556↑b
|
0.528b
|
0.537
|
0.522
|
0.531
|
se
|
0.009
|
0.009
|
0.007
|
0.008
|
0.009
|
0.008
|
0.008
|
0.006
|
0.008
|
0,010
|
0.009
|
0.008
|
0.008
|
0.008
|
H/L
|
0.187↑↑
|
0.181↑↑
|
0.155
|
0.151
|
0.149
|
0.153
|
0.155
|
0.129↓↓
|
0.163↑
|
0.158
|
0.164↑
|
0.157
|
0.146
|
0.147
|
se
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.005
|
0.004
|
0.004
|
0.004
|
0.005
|
8
|
D/L
|
0.520
|
0.561↑↑
|
0.472
|
0.492
|
0.495
|
0.487
|
0.540↑↑
|
0.458↓
|
0.504
|
0.490
|
0.505
|
0.561↑↑
|
0.543↑↑
|
0.490
|
se
|
0.012
|
0.009
|
0.008
|
0.009
|
0.008
|
0.007
|
0,010
|
0.009
|
0.009
|
0.009
|
0,010
|
0,012
|
0.008
|
0.008
|
H/L
|
0.151↓
|
0.173
|
0.165
|
0.166
|
0.162
|
0.158
|
0.176
|
0.174
|
0.156
|
0.172
|
0.163
|
0.160
|
0.165
|
0.168
|
se
|
0.004
|
0.004
|
0.003
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.003
|
0.005
|
0.005
|
0.005
|
0.004
|
0.004
|
9
|
D/L
|
0.550
|
0.557
|
0.569↑↑
|
0.570↑↑
|
0.549
|
0.535
|
0.591↑↑
|
0.520
|
0.501↓↓
|
0.535b
|
0.567↑b
|
0.543
|
0.554
|
0.542
|
se
|
0.008
|
0.008
|
0.009
|
0.008
|
0.008
|
0.007
|
0.008
|
0.006
|
0.007
|
0.008
|
0.009
|
0.008
|
0.008
|
0.008
|
H/L
|
0.176↑↑
|
0.148
|
0.160↑↑
|
0.155
|
0.151
|
0.153
|
0.166↑↑
|
0.140
|
0.160↑↑
|
0.162↑↑
|
0.156↑
|
0.146
|
0.146
|
0.139
|
se
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.005
|
0.004
|
0.004
|
0.005
|
10
|
D/L
|
0.552
|
0.552
|
0.519↓
|
0.541
|
0.521
|
0.591↑↑
|
0.586↑↑
|
0.503↓↓
|
0.508↓↓
|
0.520
|
0.534
|
0.525
|
0.515↓↓
|
0.540
|
se
|
0.009
|
0.009
|
0.008
|
0.006
|
0.008
|
0.007
|
0.011
|
0.007
|
0.007
|
0.010
|
0.010
|
0.008
|
0.008
|
0.006
|
H/L
|
0.162
|
0.172↑↑
|
0.164↑
|
0.162
|
0.154
|
0.142
|
0.160
|
0.141
|
0.151
|
0.164↑
|
0.153
|
0.165↑a
|
0.146a
|
0.153
|
se
|
0.004
|
0.005
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.005
|
0.005
|
0.004
|
0.004
|
0.005
|
11
|
D/L
|
0.522
|
0.559↑↑
|
0.538↑
|
0.519
|
0.527
|
0.529
|
0.543↑
|
0.567↑↑
|
0.525
|
0.513
|
0.532
|
0.524
|
0.541↑↑
|
0.517
|
se
|
0.007
|
0.007
|
0.008
|
0.008
|
0.008
|
0.008
|
0.009
|
0.008
|
0.008
|
0.010
|
0.009
|
0.009
|
0.008
|
0.007
|
H/L
|
0.161
|
0.159
|
0.145
|
0.164↑↑
|
0.166↑↑
|
0.151
|
0.178↑↑
|
0.174↑↑
|
0.159
|
0.162↑
|
0.172↑↑
|
0.155
|
0.168↑↑
|
0.149
|
se
|
0.004
|
0.004
|
0.003
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
18
|
D/L
|
0.549↑
|
0.513
|
0.526
|
0.531
|
0.487↓↓
|
0.531
|
0.578↑↑
|
0.515
|
0.523
|
0.534
|
0.532
|
0.492↓↓a
|
0.571↑↑a
|
0.523
|
se
|
0.009
|
0.009
|
0.008
|
0.008
|
0.009
|
0.007
|
0.008
|
0.010
|
0.007
|
0.010
|
0.011
|
0.008
|
0.008
|
0.008
|
H/L
|
0.163
|
0.166
|
0.154
|
0.166
|
0.134↓↓
|
0.153
|
0.160
|
0.166
|
0.170↑
|
0.171↑b
|
0.153b
|
0.171↑
|
0.165
|
0.159
|
se
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.003
|
0.005
|
0.004
|
0.004
|
0.004
|
0.005
|
X
|
D/L
|
0.573
|
0.583
|
0.574
|
0.578
|
0.572↓
|
0.573
|
0.569↓↓
|
0.564↓↓
|
0.564↓↓
|
0.593a
|
0.538↓↓a
|
0.537↓↓a
|
0.578a
|
0.593
|
se
|
0.008
|
0.007
|
0.008
|
0.007
|
0.008
|
0.008
|
0.007
|
0.008
|
0.007
|
0.010
|
0.007
|
0.007
|
0.009
|
0.007
|
H/L
|
0.144↑
|
0.171↑↑
|
0.137
|
0.131
|
0.141↑
|
0.147↑↑
|
0.139
|
0.128
|
0.143↑
|
0.146↑
|
0.137
|
0.161↑↑
|
0.161↑↑
|
0.130
|
se
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.005
|
0.004
|
0.004
|
0.004
|
0.004
|
Y
|
D/L
|
0.558
|
0.528↓↓
|
0.531↓↓
|
0.553
|
0.528↓↓
|
0.572↑↑
|
0.537↓↓
|
0.557
|
0.564
|
0.557b
|
0.528↓↓b
|
0.525↓↓a
|
0.580↑↑a
|
0.558
|
se
|
0.006
|
0.008
|
0.007
|
0.008
|
0.008
|
0.007
|
0.006
|
0.006
|
0.007
|
0,010
|
0.009
|
0.006
|
0.007
|
0.007
|
H/L
|
0.154↑↑
|
0.173↑↑
|
0.143
|
0.145
|
0.135
|
0.153↑↑
|
0.137
|
0.131
|
0.143
|
0.160↑↑
|
0.154↑↑
|
0.151↑↑
|
0.166↑↑
|
0.132
|
se
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.004
|
0.003
|
0.004
|
0.005
|
0.005
|
0.004
|
0.004
|
0.004
|
- Carriers: T10-T13 represent two familial cases of fathers and sons: 46,XY,t(4;5)(p15.1;p12) (T10, T11) and 46,XY,t(7;10)(p21.1;q26.13) (T12, T13). All results were compared to mean Control value obtained for 8 healthy donors. One hundred and-fifty of centromeres were counted for each male and per each chromosome. Values p < 0.01 indicated statistically significant differences (one-way ANOVA) and were marked with proper asterisks
- Asterisks used in the Table mark the power of significance
- when compared to mean Control value
- p ≤ 0.0001 (very high statistical significance)
- ↑↑ centromere localized closer to the acrosome
- ↓↓ centromere localized closer to the basal part
- p > 0.0001-p ≤ 0.01(high statistical significance)
- ↑ centromere localized closer to the acrosome
- ↓ centromere localized closer to the basal part;
- between father and son
- a p ≤ 0.0001 (very high statistical significance)
- b 0.0001 < p ≤ 0.01 (high statistical significance)