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Table 5 Summary of differences observed in radial positioning observed in familial RCT cases. Results presented in details in Table 3 and Fig. 4. ‘+’ means the difference in topology of particular centromere in cell nucleus of spermatozoa between father and son (p < 0.01)

From: Chromosome (re)positioning in spermatozoa of fathers and sons – carriers of reciprocal chromosome translocation (RCT)

RCT

Chromosome

4

7

8

9

10

11

18

X

Y

T10

T11

t(4;5) father

t(4;5) son

+

+

 

+

  

+

+

+

Direction of repositioning

S-c

S-c

 

S-a

  

S-c

S-c

S-c

T12

T13

t(7;10) father

t(7;10) son

    

+

 

+

+

+

Direction of repositioning

    

F-p

 

F-c

F-c

F-c

  1. S-c: positions of centromeres localized more central in spermatozoa of son when compared to father
  2. S-a: positions of centromeres localized more acrosomal in spermatozoa of son when compared to father
  3. F-p: positions of centromeres localized more peripheral in spermatozoa of father when compared to son
  4. F-c: positions of centromeres localized more central in spermatozoa of father when compared to son
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BMC Medical Genomics

ISSN: 1755-8794

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