Table 3 Results of gene-based, low-frequency variant association tests (significance level P = 7.81 × 10−4)
From: Identification of sequence variants associated with severe microtia-astresia by targeted sequencing
| Gene | Markers | P-value |
|---|---|---|
| PLEC | 12 | 1.40 × 10−10 |
| USH2A | 16 | 1.11 × 10−08 |
| FREM2 | 6 | 4.38 × 10−05 |
| DCHS1 | 6 | 0.000288 |
| GLI3 | 5 | 0.000297 |
| POMT1 | 2 | 0.000297 |
