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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets

Fig. 1

Schematic of experimental outline and EGF time course. a EGF was added to HER2+ SKBR3 cells for indicated times. Total RNA, protein or chromatin (*) was harvested for the indicated times. b Abundance of proteins involved in EGFR signaling were immunoblotted (n = 2 repeats). c Levels of known immediate early genes (IEGs) were assayed by qPCR during an EGF time course (n = 3 repeats). *p-value < 0.1, **p-value < .01, ***p-value < .001 one-sided t-test for significant difference between Untreated and EGF treated samples

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