Table 3 Change in plasma levels of adiponectin, chimerine, TNF-a and IL-6 in the study groups of patients

Groups

1

2

3

4

5

6

7

8

TNA-a

pg/ml

2,03 (1,46 – 3,72)

1,92 (1,43 – 2,15)

p_1–2 = 0,47

4,07 (3,37 – 8,56)

p_1–3 = 0,03*

p_2–3 < 0,01*

20,16 (15,5 – 22,08)

p_1–4 < 0,01*

p_2–4 < 0,01*

p_3–4 < 0,01*

10,82 (5,68 – 13,89)

p_1–5 < 0,01*

p_2–5 < 0,01*

p_3–5 = 0,05

p_4–5 < 0,01*

28,21 (19,2 – 40,19)

p_1–6 < 0,01*

p_2–6 < 0,01*

p_3–6 < 0,01*

p_4–6 = 0,02*

p_5–6 < 0,01*

14,71 (9,63 – 17,3)

p_1–7 < 0,01*

p_2–7 < 0,01*

p_3–7 < 0,01*

p_4–7 = 0,69

p_5–7 = 0,06

p_6–7 < 0,01*

32,86 (29,9 –34,16)

p_1–8 < 0,01*

p_2–8 < 0,01*

p_3–8 < 0,01*

p_4–8 < 0,01*

p_5–8 < 0,01*

p_6–8 = 0,84

p_7–8 < 0,01*

Chemerin

ng/ml

128 (117–147)

128,5 (103–157,5)

p_1–2 = 0,99

166 (147–172)

p_1–3 = 0,04*

p_2–3 = 0,03*

170,5 (151,5 – 179,5)

p_1–4 = 0,04*

p_2–4 = 0,04*

p_3–4 = 0,44

169 (148–177)

p_1–5 = 0,01*

p_2–5 = 0,03*

p_3–5 = 0,47

p_4–5 = 0,93

150 (130,5 – 175,5)

p_1–6 = 0,10

p_2–6 = 0,17

p_3–6 = 0,75

p_4–6 = 0,38

p_5–6 = 0,53

190 (180–196)

p_1–7 < 0,01*

p_2–7 < 0,01*

p_3–7 = 0,04*

p_4–7 = 0,06

p_5–7 = 0,049*

p_6–7 = 0,02*

143 (134–158)

p_1–8 = 0,05

p_2–8 = 0,18

p_3–8 = 0,26

p_4–8 = 0,28

p_5–8 = 0,16

p_6–8 = 0,75

p_7–8 < 0,01*

Adiponectin

mkg/ml

3,54 (2,59 – 4,27)

1,74 (1,29 – 4,16)

p_1–2 = 0,18

2,27 (1,8 – 4,19)

p_1–3 = 0,25

p_2–3 = 0,32

3,81 (2,87 – 4,14)

p_1–4 = 0,84

p_2–4 = 0,15

p_3–4 = 0,25

4,5 (1,9 – 5,48)

p_1–5 = 0,61

p_2–5 = 0,07

p_3–5 = 0,27

p_4–5 = 0,99

3,67 (2,92–5,18)

p_1–6 = 0,61

p_2–6 = 0,07

p_3–6 = 0,28

p_4–6 = 0,99

p_5–6 = 0,98

4,44 (2,87–5,21)

p_1–7 = 0,39

p_2–7 = 0,03*

p_3–7 = 0,15

p_4–7 = 0,70

p_5–7 = 0,69

p_6–7 = 0,69

3,86 (1,85 – 4,71)

p_1–8 = 0,85

p_2–8 = 0,11

p_3–8 = 0,37

p_4–8 = 0,88

p_5–8 = 0,65

p_6–8 = 0,65

p_7–8 = 0,49

CRP

mmol/l

4,41 (3,12–5,38)

1,8 (1,51 – 4,78)

p_1–2 = 0,058

1,9 (1,03 – 2,83)

7,72 (4,6 – 8,88)

7,6 (2,2 – 13,4)

5,7 (5,52 – 9,24)

p_2–6 = 0,036*

13,4 (9,9 – 15,99)

p_1–7 = 0,004*

p_2–7 = 0,0017*

p_3–7 = 0,01*

8,95 (5,04 – 14,34)

p_1–8 = 0,045*

p_2–8 = 0,004*

Glucose

mmol/l

3,75 (1,7 – 5,24)

5,18 (4,98 – 5,34)

p_1–2 = 0,01*

5,6 (5,2 – 5,83)

p_1–3 = 0,02*

10,74 (9,74 – 10,88)

p_1–4 = 0,003*

5,8 (5,6 – 6,3)

p_1–5 = 0,002*

8,1 (6,7 – 11,8)

p_1–6 = 0,007*

5,9 (5,5 – 6,6)

p_1–7 = 0,01*

7,1 (5,8 – 9,6)

p_1–8 = 0,005*

Insulin

ng/ml

47,09 (27,16 - 87,18)

45,06 (16,93 - 76,40)

60,62 (30,77 - 90,83)

84,67 (42,03 - 135,37)

176 (124–248)

p = 0,01

139 (119–476)

p = 0,035

216 (94,38 - 371,6)

p = 0,033

304 (244–616)

p = 0,001