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Table 4 Change in the number of copies of mtDNA in the study groups of patients in tissues of different locations (Copies per cell)

From: Interrelation of chemerin and TNF-α with mtDNA copy number in adipose tissues and blood cells in obese patients with and without type 2 diabetes

  Control group Pre-obese Patients with obesity
BMI, kg/m2 18,5 – 24,9 25–29,9 grade I obesity (30–34,9) grade II obesity (35–39,9) grade III obesity (› 40)
Without T2DM With T2DM Without T2DM With T2DM Without T2DM With T2DM
Groups 1 2 3 4 5 6 7 8
GO 855 (744–993) 997 (592–1275)
p1–2 = 0,76
703 (298–1293)
p1–3 = 0,73
p2–3 = 0,66
590 (541–633)
p1–4 = 0,18
p2–4 = 0,19
p3–4 = 0,81
947 (503–1758)
p1–5 = 0,35
p2–5 = 0,57
p3–5 = 0,20
p4–5 = 0,20
1619 (963–2228)
p1–6 = 0,08
p2–6 = 0,29
p3–6 = 0,10
p4–6 = 0,01*
p5–6 = 0,46
733 (465–834)
p1–7 = 0,63
p2–7 = 0,33
p3–7 = 0,62
p4–7 = 0,56
p5–7 = 0,24
p6–7 = 0,02*
1080 (769–1663)
p1–8 = 0,28
p2–8 = 0,33
p3–8 = 0,09
p4–8 = 0,03*
p5–8 = 0,78
p6–8 = 0,15
p7–8 = 0,03*
Mes 791 (637–1031) 841 (549–1160)
p1–2 = 0,74
632 (530–765)
p1–3 = 0,50
p2–3 = 0,20
993,500 (615–2257)
p1–4 = 0,35
p2–4 = 0,83
p3–4 = 0,20
1132(1044–1325)
p1–5 = 0,06
p2–5 = 0,08
p3–5 = 0,01*
p4–5 = 0,56
1630 (1360–1835)
p1–6 = 0,08
p2–6 = 0,01*
p3–6 < 0,01*
p4–6 = 0,28
p5–6 = 0,06
900 (637–960)
p1–7 = 0,12
p2–7 = 0,91
p3–7 = 0,04*
p4–7 = 0,73
p5–7 = 0,02*
p6–7 < 0,01*
925 (711–1653)
p1–8 = 0,07
p2–8 = 0,25
p3–8 = 0,01*
p4–8 = 0,98
p5–8 = 0,50
p6–8 = 0,07
p7–8 = 0,14
SAT 462 (316–820) 627 (569,5–911)
p1–2 = 0,07
527 (402–759)
p1–3 = 0,71
p2–3 = 0,36
1206,5 (533–1820)
p1–4 = 0,14
p2–4 = 0,46
p3–4 = 0,33
460 (346–1909)
p1–5 = 0,56
p2–5 = 0,29
p3–5 = 0,96
p4–5 = 0,57
931 (642–3855)
p1–6 = 0,07
p2–6 = 0,22
p3–6 = 0,15
p4–6 = 0,70
p5–6 = 0,17
613 (568–862)
p1–7 = 0,09
p2–7 = 0,71
p3–7 = 0,45
p4–7 = 0,39
p5–7 = 0,37
p6–7 = 0,13
1059 (635–2484)
p1–8 < 0,01*
p2–8 = 0,13
p3–8 = 0,03*
p4–8 = 0,52
p5–8 = 0,02*
p6–8 = 0,96
p7–8 = 0,01*
MNC 224,5 (159,7 – 315,5) 323(180–414)
p1–2 = 0,06
149 (126–242)
p1–3 = 0,27
p2–3 = 0,02*
296(163–429)
p1–4 = 0,56
p2–4 = 0,87
p3–4 = 0,18
145 (139–209)
p1–5 = 0,17
p2–5 = 0,01*
p3–5 = 0,90
p4–5 = 0,23
102 (89–141)
p1–6 = 0,02*
p2–6 < 0,01*
p3–6 = 0,13
p4–6 = 0,16
p5–6 = 0,06
177 156 (113–229)
p1–8 = 0,13
p2–8 < 0,01*
p3–8 = 0,96
p4–8 = 0,21
p5–8 = 0,98
p6–8 = 0,06
p7–8 = 0,47