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Table 4 Change in the number of copies of mtDNA in the study groups of patients in tissues of different locations (Copies per cell)

From: Interrelation of chemerin and TNF-α with mtDNA copy number in adipose tissues and blood cells in obese patients with and without type 2 diabetes

  Control group Pre-obese Patients with obesity
BMI, kg/m2 18,5 – 24,9 25–29,9 grade I obesity (30–34,9) grade II obesity (35–39,9) grade III obesity (› 40)
Without T2DM With T2DM Without T2DM With T2DM Without T2DM With T2DM
Groups 1 2 3 4 5 6 7 8
GO 855 (744–993) 997 (592–1275) p1–2 = 0,76 703 (298–1293) p1–3 = 0,73 p2–3 = 0,66 590 (541–633) p1–4 = 0,18 p2–4 = 0,19 p3–4 = 0,81 947 (503–1758) p1–5 = 0,35 p2–5 = 0,57 p3–5 = 0,20 p4–5 = 0,20 1619 (963–2228) p1–6 = 0,08 p2–6 = 0,29 p3–6 = 0,10 p4–6 = 0,01* p5–6 = 0,46 733 (465–834) p1–7 = 0,63 p2–7 = 0,33 p3–7 = 0,62 p4–7 = 0,56 p5–7 = 0,24 p6–7 = 0,02* 1080 (769–1663) p1–8 = 0,28 p2–8 = 0,33 p3–8 = 0,09 p4–8 = 0,03* p5–8 = 0,78 p6–8 = 0,15 p7–8 = 0,03*
Mes 791 (637–1031) 841 (549–1160) p1–2 = 0,74 632 (530–765) p1–3 = 0,50 p2–3 = 0,20 993,500 (615–2257) p1–4 = 0,35 p2–4 = 0,83 p3–4 = 0,20 1132(1044–1325) p1–5 = 0,06 p2–5 = 0,08 p3–5 = 0,01* p4–5 = 0,56 1630 (1360–1835) p1–6 = 0,08 p2–6 = 0,01* p3–6 < 0,01* p4–6 = 0,28 p5–6 = 0,06 900 (637–960) p1–7 = 0,12 p2–7 = 0,91 p3–7 = 0,04* p4–7 = 0,73 p5–7 = 0,02* p6–7 < 0,01* 925 (711–1653) p1–8 = 0,07 p2–8 = 0,25 p3–8 = 0,01* p4–8 = 0,98 p5–8 = 0,50 p6–8 = 0,07 p7–8 = 0,14
SAT 462 (316–820) 627 (569,5–911) p1–2 = 0,07 527 (402–759) p1–3 = 0,71 p2–3 = 0,36 1206,5 (533–1820) p1–4 = 0,14 p2–4 = 0,46 p3–4 = 0,33 460 (346–1909) p1–5 = 0,56 p2–5 = 0,29 p3–5 = 0,96 p4–5 = 0,57 931 (642–3855) p1–6 = 0,07 p2–6 = 0,22 p3–6 = 0,15 p4–6 = 0,70 p5–6 = 0,17 613 (568–862) p1–7 = 0,09 p2–7 = 0,71 p3–7 = 0,45 p4–7 = 0,39 p5–7 = 0,37 p6–7 = 0,13 1059 (635–2484) p1–8 < 0,01* p2–8 = 0,13 p3–8 = 0,03* p4–8 = 0,52 p5–8 = 0,02* p6–8 = 0,96 p7–8 = 0,01*
MNC 224,5 (159,7 – 315,5) 323(180–414) p1–2 = 0,06 149 (126–242) p1–3 = 0,27 p2–3 = 0,02* 296(163–429) p1–4 = 0,56 p2–4 = 0,87 p3–4 = 0,18 145 (139–209) p1–5 = 0,17 p2–5 = 0,01* p3–5 = 0,90 p4–5 = 0,23 102 (89–141) p1–6 = 0,02* p2–6 < 0,01* p3–6 = 0,13 p4–6 = 0,16 p5–6 = 0,06 177 156 (113–229) p1–8 = 0,13 p2–8 < 0,01* p3–8 = 0,96 p4–8 = 0,21 p5–8 = 0,98 p6–8 = 0,06 p7–8 = 0,47