Fig. 2

Dependence of inducible reporter expression on the number of NFkB binding sites present in the promoter cassette in primary human T cells (a) and CAR NK-92 cells (b). Relative mCherry fluorescence values (copGFP-normalized) are shown as solid lines (15 h post activation) and dashed lines (T cells incubated for 15 h without beads or CAR NK-92 cells incubated with PSMA-negative non-target HEK293T cells). AFU – arbitrary fluorescence units